Oncological Outcomes of Primary vs. Salvage OPHL Type II: A Systematic Review

Carmelo Saraniti, Barbara Verro, Francesco Ciodaro and Francesco Galletti
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Carmelo Saraniti: ENT Clinic, Department of Biomedicine, Neuroscience and Advanced Diagnostic, University of Palermo, 90127 Palermo, Italy
Barbara Verro: ENT Clinic, Department of Biomedicine, Neuroscience and Advanced Diagnostic, University of Palermo, 90127 Palermo, Italy
Francesco Ciodaro: Division for Otorhinolaryngology, Department of Adult and Development Age Human Pathology “Gaetano Barresi”, University of Messina, 98125 Messina, Italy
Francesco Galletti: Division for Otorhinolaryngology, Department of Adult and Development Age Human Pathology “Gaetano Barresi”, University of Messina, 98125 Messina, Italy

IJERPH, 2022, vol. 19, issue 3, 1-11

Abstract: Background: Open partial horizontal laryngectomy type II (OPHL type II) has two main aims: oncological radicality and laryngeal preservation. The aim of this review is to define and emphasize the oncological efficacy of OPHL type II, both as primary and salvage surgery, by analyzing the latest literature. Methods: The research was carried out on Pubmed, Scopus and Web of Science databases, by using strict keywords. Oncological outcomes were evaluated by the following parameters: overall survival, disease-specific survival, disease-free survival, local control, laryngeal preservation, local recurrence. Results: The review included 19 articles divided into three groups: (1) primary OPHL type II, (2) salvage OPHL type II, (3) adjuvant radiotherapy after primary OPHL type II. The articles showed excellent results as far as oncological radicality and organ preservation. Conclusions: This review demonstrated that OPHL type II is useful to obtain oncological radicality both as primary surgery and salvage surgery. Nevertheless, the only criterion that determined the positive outcome and efficacy of this technique is the strict selection of patient and tumor.

Keywords: otolaryngology; head and neck; laryngectomy; surgical oncology; salvage therapy (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2022
References: View references in EconPapers View complete reference list from CitEc
Citations: View citations in EconPapers (1)

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