Radial-EBUS: CryoBiopsy Versus Conventional Biopsy: Time-Sample and C-Arm

Paul Zarogoulidis, Christoforos S. Kosmidis, Wolfgang Hohenforst-Schmidt, Dimitrios Matthaios, Konstantinos Sapalidis, Dimitrios Petridis, Eleni-Isidora Perdikouri, Nikos Courcoutsakis, Dimitris Hatzibougias, Christos Arnaoutoglou, Lutz Freitag, Aristeidis Ioannidis, Haidong Huang, Christos Tolis, Chong Bai and J. Francis Turner
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Paul Zarogoulidis: Pulmonary-Oncology Department, General Clinic Euromedica, Private Hospital, 54645 Thessaloniki, Greece
Christoforos S. Kosmidis: Surgical Department, University Hospital of Thessaloniki AHEPA, Aristotle University of Thessaloniki (AUTH), 1st St. Kiriakidi Street, 54621 Thessaloniki, Greece
Wolfgang Hohenforst-Schmidt: Sana Clinic Group Franken, Department of Cardiology/Pulmonology/Intensive Care/Nephrology, “Hof” Clinics, University of Erlangen, 91052 Hof, Germany
Dimitrios Matthaios: Department of Medical Oncology, Rhodes General Hospital, 85133 Rhodes, Greece
Konstantinos Sapalidis: Surgical Department, University Hospital of Thessaloniki AHEPA, Aristotle University of Thessaloniki (AUTH), 1st St. Kiriakidi Street, 54621 Thessaloniki, Greece
Dimitrios Petridis: Department of Food Science and Technology, International Hellenic University, 54621 Thessaloniki, Greece
Eleni-Isidora Perdikouri: Oncology Department, General Hospital of Volos, 38222 Volos, Greece
Nikos Courcoutsakis: Department of Radiology and Medical Imaging, University Hospital of Alexandroupolis, Democritus University of Thrace, 68100 Alexandroupolis, Greece
Dimitris Hatzibougias: Private Pathology Laboratory, “Microdiagnostics”, 54621 Thessaloniki, Greece
Christos Arnaoutoglou: Department of Obstetrics & Gynecology, Papageorgiou Hospital, Aristotle University of Thessaloniki, 54621 Thessaloniki, Greece
Lutz Freitag: Pulmonary Department, University Hospital of Zurich, 8004 Zurich, Switzerland
Aristeidis Ioannidis: Department of Respiratory & Critical Care Medicine, Changhai Hospital, The Second Military Medical University, Shanghai 200001, China
Haidong Huang: Department of Respiratory & Critical Care Medicine, Changhai Hospital, The Second Military Medical University, Shanghai 200001, China
Christos Tolis: Oncoderm Private Oncology Clinic, 45221 Ioannina, Greece
Chong Bai: Department of Respiratory & Critical Care Medicine, Changhai Hospital, The Second Military Medical University, Shanghai 200001, China
J. Francis Turner: Department of Medicine, University of Tennessee Graduate School of Medicine, Knoxville, TN 37001, USA

IJERPH, 2022, vol. 19, issue 6, 1-11

Abstract: Introduction: Diagnosis of lung nodules is still under investigation. We use computed tomography scans and positron emission tomography in order to identify their origin. Patients and Methods: In our retrospective study, we included 248 patients with a single lung nodule or multiple lung nodules of size ≥1 cm. We used a radial-endobronchial ultrasound and a C-Arm. We used a 1.1 mm cryoprobe versus a 22G needle vs. forceps/brush. We compared the sample size of each biopsy method with the number of cell-block slices. Results: Central lesions indifferent to the method provided the same mean number of cell-block slices (0.04933–0.02410). Cryobiopsies provide less sample size for peripheral lesions due to the higher incidence of pneumothorax (0.04700–0.02296). Conclusion: The larger the lesion ≥2 cm, and central, more cell-blocks are produced indifferent to the biopsy method (0.13386–0.02939). The time of the procedure was observed to be less when the C-Arm was used as an additional navigation tool (0.14854–0.00089).

Keywords: radial-ebus; bronchoscopy; forceps; brush; cell-blocks; lung cancer; cryobiopsy (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2022
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