Nano-Hydroxyapatite (nHAp) in the Remineralization of Early Dental Caries: A Scoping Review

Aiswarya Anil, Wael I. Ibraheem, Abdullah A. Meshni, Reghunathan S. Preethanath and Sukumaran Anil
Additional contact information
Aiswarya Anil: Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai 602105, India
Wael I. Ibraheem: College of Dentistry, Jazan University, P.O. Box 114, Jazan 45142, Saudi Arabia
Abdullah A. Meshni: College of Dentistry, Jazan University, P.O. Box 114, Jazan 45142, Saudi Arabia
Reghunathan S. Preethanath: College of Dentistry, Jazan University, P.O. Box 114, Jazan 45142, Saudi Arabia
Sukumaran Anil: Oral Health Institute, Department of Dentistry, Hamad Medical Corporation, Doha 3050, Qatar

IJERPH, 2022, vol. 19, issue 9, 1-14

Abstract: (1) Background: Nano-hydroxyapatite (nHAp) has been reported to have a remineralizing effect on early carious lesions. The objective of this scoping review was to analyze the remineralization potential of nano-hydroxyapatite (nHAp)-containing dentifrices, by mapping the existing literature. (2) Methods: This review was performed using the PRISMA-ScR Checklist, which is an extension of the PRISMA Checklist for Systematic Reviews and Meta-Analyses. In this study, the population, concept, and context (PCC) framework was used to find relevant papers published between 2010 and 2021. Nano-hydroxyapatite (nHAp) and dentifrices containing nHAp as one of the ingredients were the two main concepts of the research question. MeSH phrases, keywords, and other free terms relevant to nano-hydroxyapatite and dentifrices were used to search the literature databases. (3) Results: Preliminary searches yielded 59 studies; the title and abstract screening results excluded 11 studies. The remaining studies were thoroughly reviewed by two reviewers on the basis of the inclusion and exclusion criteria. Finally, 28 studies were included, and 20 studies were excluded. Most of the studies that were included reported that when nHAp was used alone, it had many different effects, such as remineralization, caries prevention, less demineralization, brighter teeth, less pain, and remineralization of enamel after orthodontic debonding. (4) Conclusions: Dentifrices that contain nHAp offer a variety of therapeutic and preventative effects. Currently, there is insufficient evidence to support the efficacy of nHAp dentifrices in primary teeth. Additional long-term investigations using standardized protocols are required to reach decisive conclusions about the effects of nHAp dentifrices on primary and permanent dentitions.

Keywords: nano-hydroxyapatite; dentifrices; scoping review; dental caries; remineralization; demineralization (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2022
References: View complete reference list from CitEc
Citations:

Downloads: (external link)
https://www.mdpi.com/1660-4601/19/9/5629/pdf (application/pdf)
https://www.mdpi.com/1660-4601/19/9/5629/ (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:gam:jijerp:v:19:y:2022:i:9:p:5629-:d:809020

Access Statistics for this article

IJERPH is currently edited by Ms. Jenna Liu

More articles in IJERPH from MDPI
Bibliographic data for series maintained by MDPI Indexing Manager ().