Autofluorescence Image-Guided Endoscopy in the Management of Upper Aerodigestive Tract Tumors

Norhafiza Mat Lazim (), Abdul Hafeez Kandhro, Anna Menegaldo, Giacomo Spinato, Barbara Verro and Baharudin Abdullah
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Norhafiza Mat Lazim: Department of Otorhinolaryngology-Head and Neck Surgery, School of Medical Sciences, Universiti Sains Malaysia, Health Campus, Kubang Kerian 16150, Malaysia
Abdul Hafeez Kandhro: Institute of Medical Technology, Jinnah Sindh Medical University, Karachi 75510, Pakistan
Anna Menegaldo: Department of Neurosciences, Section of Otolaryngology and Regional Centre for Head and Neck Cancer, University of Padova, 31100 Treviso, Italy
Giacomo Spinato: Department of Neurosciences, Section of Otolaryngology and Regional Centre for Head and Neck Cancer, University of Padova, 31100 Treviso, Italy
Barbara Verro: Division of Otorhinolaryngology, Department of Biomedicine, Neuroscience and Advanced Diagnostic, University of Palermo, 90127 Palermo, Italy
Baharudin Abdullah: Department of Otorhinolaryngology-Head and Neck Surgery, School of Medical Sciences, Universiti Sains Malaysia, Health Campus, Kubang Kerian 16150, Malaysia

IJERPH, 2022, vol. 20, issue 1, 1-18

Abstract: At this juncture, autofluorescence and narrow-band imaging have resurfaced in the medicine arena in parallel with current technology advancement. The emergence of newly developed optical instrumentation in addition to the discovery of new fluorescence biomolecules have contributed to a refined management of diseases and tumors, especially in the management of upper aerodigestive tract tumors. The advancement in multispectral imaging and micro-endoscopy has also escalated the trends further in the setting of the management of this tumor, in order to gain not only the best treatment outcomes but also facilitate early tumor diagnosis. This includes the usage of autofluorescence endoscopy for screening, diagnosis and treatment of this tumor. This is crucial, as microtumoral deposit at the periphery of the gross tumor can be only assessed via an enhanced endoscopy and even more precisely with autofluorescence endoscopic techniques. Overall, with this new technique, optimum management can be achieved for these patients. Hence, the treatment outcomes can be improved and patients are able to attain better prognosis and survival.

Keywords: head and neck cancers; autofluorescence; narrow band imaging; surgical margins; endoscopy; upper aerodigestive tract tumor; oral cavity carcinoma; squamous cell carcinoma (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2022
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