Diabetes-Related Lower Extremity Amputations in Romania: Patterns and Changes between 2015 and 2019

Horaţiu Coman, Bogdan Stancu (), Norina A. Gâvan, Frank L. Bowling, Laura Podariu, Cosmina I. Bondor and Gabriela Radulian
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Horaţiu Coman: Vascular Surgery Clinic, Cluj County Emergency Hospital, 400347 Cluj-Napoca, Romania
Bogdan Stancu: Second Department of Surgery, “Iuliu Haţieganu” University of Medicine and Pharmacy, 400006 Cluj-Napoca, Romania
Norina A. Gâvan: Wörwag Pharma Romania SRL, 400267 Cluj-Napoca, Romania
Frank L. Bowling: Developmental Biomedicine Research Group, The University of Manchester, Manchester M13 9PL, UK
Laura Podariu: Vascular Surgery Clinic, Cluj County Emergency Hospital, 400347 Cluj-Napoca, Romania
Cosmina I. Bondor: Department of Medical Informatics and Biostatistics, “Iuliu Haţieganu” University of Medicine and Pharmacy, 400349 Cluj-Napoca, Romania
Gabriela Radulian: Department of Internal Medicine, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucureşti, Romania

IJERPH, 2022, vol. 20, issue 1, 1-13

Abstract: Lower extremity amputations (LEAs) are a feared complication of diabetes mellitus (DM). Here we evaluated the recent trends in DM-related LEAs in Romania. We collected data from a national database regarding minor and major LEAs performed between 2015 and 2019 in patients with DM admitted to a public hospital. Absolute numbers of LEAs were presented by year, diabetes type, sex and age; incidence rates of LEAs in the general population were also calculated. Over the study period, 40,499 LEAs were recorded nationwide (83.16% in persons with type 2 DM [T2DM]); on average, the number of LEAs increased by 5.7%/year. This trend was driven by an increased number of LEAs in patients with T2DM; in patients with type 1 DM (T1DM), LEAs decreased over the study period. In patients with T2DM, the increase in minor LEAs was more pronounced than that in major LEAs. The overall number of LEAs showed an increasing trend with age (r = 0.72), which was most pronounced in patients aged ≥70 years. Men had a higher frequency of LEAs than women, regardless of DM type. These data support renewed efforts to prevent and decrease the burden of amputations among patients with DM.

Keywords: diabetes mellitus; lower extremity amputation; incidence; nationwide study (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2022
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