Time Trends in Ischemic Heart Disease Mortality Attributable to PM 2.5 Exposure in Southeastern China from 1990 to 2019: An Age-Period-Cohort Analysis

Weiwei Wang, Nan Zhou, Hao Yu, Huafeng Yang, Jinyi Zhou and Xin Hong ()
Additional contact information
Weiwei Wang: Department of Non-Communicable Disease Prevention, Nanjing Municipal Center for Disease Control and Prevention, 3 Zizhulin Road, Gulou District, Nanjing 210003, China
Nan Zhou: Department of Non-Communicable Disease Prevention, Nanjing Municipal Center for Disease Control and Prevention, 3 Zizhulin Road, Gulou District, Nanjing 210003, China
Hao Yu: Department of Non-Communicable Disease Prevention, Jiangsu Provincial Center for Disease Control and Prevention, 172 Jiangsu Road, Gulou District, Nanjing 210009, China
Huafeng Yang: Department of Non-Communicable Disease Prevention, Nanjing Municipal Center for Disease Control and Prevention, 3 Zizhulin Road, Gulou District, Nanjing 210003, China
Jinyi Zhou: Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, 101 Longmian Avenue, Jiangning District, Nanjing 211166, China
Xin Hong: Department of Non-Communicable Disease Prevention, Nanjing Municipal Center for Disease Control and Prevention, 3 Zizhulin Road, Gulou District, Nanjing 210003, China

IJERPH, 2023, vol. 20, issue 2, 1-11

Abstract: PM 2.5 exposure is a major environmental risk factor for the mortality of ischemic heart disease (IHD). This study aimed to analyze trends in IHD mortality attributable to PM 2.5 exposure in Jiangsu Province, China, from 1990 to 2019, and their correlation with age, period, and birth cohort. Methods: Data were extracted from the Global Burden of Disease study 2019 (GBD2019). The magnitude and direction of the trends in IHD mortality attributable to PM 2.5 exposure were analyzed by Joinpoint regression. The age-period-cohort (APC) model was used to evaluate the cohort and period effect. Results: Age-standardized mortality rate (ASMR) of IHD attributable to PM 2.5 exposure decreased from 1990 to 2019, with an average annual percentage change (AAPC) of −1.71% (95%CI: −2.02~−1.40), which, due to ambient PM 2.5 (APM) exposure and household PM 2.5 (HPM) exposure increased with AAPCs of 1.45% (95%CI: 1.18~1.72) and −8.27% (95%CI: −8.84~−7.69), respectively. APC analysis revealed an exponential distribution in age effects on IHD mortality attributable to APM exposure, which rapidly increased in the elderly. The risk for IHD mortality due to HPM exposure showed a decline in the period and cohort effects, which, due to APM, increased in the period and cohort effects. However, favorable period effects were found in the recent decade. The overall net drift values for APM were above zero, and were below zero for HPM. The values for local drift with age both for APM and HPM exposures were initially reduced and then enhanced. Conclusion: The main environmental risk factor for IHD mortality changed from HPM to APM exposure in Jiangsu Province, China. Corresponding health strategies and prevention management should be adopted to reduce ambient air pollution and decrease the effects of APM exposure on IHD mortality.

Keywords: PM 2.5; ambient PM 2.5; household PM 2.5; ischemic heart disease; age-period-cohort analysis (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2023
References: View complete reference list from CitEc
Citations:

Downloads: (external link)
https://www.mdpi.com/1660-4601/20/2/973/pdf (application/pdf)
https://www.mdpi.com/1660-4601/20/2/973/ (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:gam:jijerp:v:20:y:2023:i:2:p:973-:d:1025872

Access Statistics for this article

IJERPH is currently edited by Ms. Jenna Liu

More articles in IJERPH from MDPI
Bibliographic data for series maintained by MDPI Indexing Manager ().