Global Trends of Lipid Metabolism Research in Epigenetics Field: A Bibliometric Analysis from 2012–2021

Hanqi Liu, Yanqing Huang, Shanshan Lu, Didi Yuan and Junwen Liu ()
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Hanqi Liu: Department of Histology and Embryology, Xiangya School of Medicine, Central South University, Changsha 410013, China
Yanqing Huang: Department of Histology and Embryology, Xiangya School of Medicine, Central South University, Changsha 410013, China
Shanshan Lu: Department of Histology and Embryology, Xiangya School of Medicine, Central South University, Changsha 410013, China
Didi Yuan: Department of Histology and Embryology, Xiangya School of Medicine, Central South University, Changsha 410013, China
Junwen Liu: Department of Histology and Embryology, Xiangya School of Medicine, Central South University, Changsha 410013, China

IJERPH, 2023, vol. 20, issue 3, 1-18

Abstract: Most common diseases are characterized by metabolic changes, among which lipid metabolism is a hotspot. Numerous studies have demonstrated a strong correlation between epigenetics and lipid metabolism. This study of publications on the epigenetics of lipid metabolism searched in the Web of Science Core Collection from 2012 to 2022, and a total of 3685 publications were retrieved. Much of our work focused on collecting the data of annual outputs, high-yielding countries and authors, vital journals, keywords and citations for qualitative and quantitative analysis. In the past decade, the overall number of publications has shown an upward trend. China (1382, 26.69%), the United States (1049, 20.26%) and Italy (206, 3.98%) were the main contributors of outputs. The Chinese Academy of Sciences and Yale University were significant potential cooperation institutions. Articles were mainly published in the “International Journal of Molecular Sciences”. In addition to typical liver-related diseases, “ferroptosis”, “diabetes” and “atherosclerosis” were identified as potential research topics. “NF-κB” and “oxidative stress” were referred to frequently in publications. METTL3 and ALKBH5 were the most discussed m 6 A-related enzymes in 2022. Our study revealed research hotspots and new trends in the epigenetics of lipid metabolism, hoping to provide significant information and inspiration for researchers to further explore new directions.

Keywords: lipid metabolism; epigenetics; bibliometrics; CiteSpace; VOSviewer (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2023
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