Body Mass Index and Late Adverse Outcomes after a Carotid Endarterectomy

Danka Vukašinović, Miloš Maksimović (), Slobodan Tanasković, Jelena M. Marinković, Đorđe Radak, Jadranka Maksimović, Isidora Vujčić, Nebojša Prijović and Hristina Vlajinac
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Danka Vukašinović: Institute of Hygiene and Medical Ecology, Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia
Miloš Maksimović: Institute of Hygiene and Medical Ecology, Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia
Slobodan Tanasković: Vascular Surgery Clinic, “Dedinje” Cardiovascular Institute, 11000 Belgrade, Serbia
Jelena M. Marinković: Institute of Medical Statistics and Informatics, Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia
Đorđe Radak: Vascular Surgery Clinic, “Dedinje” Cardiovascular Institute, 11000 Belgrade, Serbia
Jadranka Maksimović: Institute of Epidemiology, Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia
Isidora Vujčić: Institute of Epidemiology, Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia
Nebojša Prijović: Clinic of Urology, University Clinical Center of Serbia, 11000 Belgrade, Serbia
Hristina Vlajinac: Institute of Epidemiology, Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia

IJERPH, 2023, vol. 20, issue 3, 1-10

Abstract: A cohort study was conducted to examine the association of an increased body mass index (BMI) with late adverse outcomes after a carotid endarterectomy (CEA). It comprised 1597 CEAs, performed in 1533 patients at the Vascular Surgery Clinic in Belgrade, from 1 January 2012 to 31 December 2017. The follow-up lasted four years after CEA. Data for late myocardial infarction and stroke were available for 1223 CEAs, data for death for 1305 CEAs, and data for restenosis for 1162 CEAs. Logistic and Cox regressions were used in the analysis. The CEAs in patients who were overweight and obese were separately compared with the CEAs in patients with a normal weight. Out of 1223 CEAs, 413 (33.8%) were performed in patients with a normal weight, 583 (47.7%) in patients who were overweight, and 220 (18.0%) in patients who were obese. According to the logistic regression analysis, the compared groups did not significantly differ in the frequency of myocardial infarction, stroke, and death, as late major adverse outcomes (MAOs), or in the frequency of restenosis. According to the Cox and logistic regression analyses, BMI was neither a predictor for late MAOs, analyzed separately or all together, nor for restenosis. In conclusion, being overweight and being obese were not related to the occurrence of late adverse outcomes after a carotid endarterectomy.

Keywords: body mass index; carotid endarterectomy; late outcomes; overweight; obesity (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2023
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