Methods and Strategies for Biomonitoring in Occupational Exposure to Plant Protection Products Containing Glyphosate

Horațiu Moldovan, Silvia Imre, Radu Corneliu Duca and Lénárd Farczádi ()
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Horațiu Moldovan: Department of Occupational Medicine, Faculty of Medicine, George Emil Palade University of Medicine, Pharmacy, Science, and Technology, 540142 Târgu Mureş, Romania
Silvia Imre: Center for Advanced Medical and Pharmaceutical Research, George Emil Palade University of Medicine, Pharmacy, Science, and Technology, 540142 Târgu Mureş, Romania
Radu Corneliu Duca: Environmental Hygiene and Biological Monitoring Unit, Department of Health Protection, National Health Laboratory (LNS), 3555 Dudelange, Luxembourg
Lénárd Farczádi: Center for Advanced Medical and Pharmaceutical Research, George Emil Palade University of Medicine, Pharmacy, Science, and Technology, 540142 Târgu Mureş, Romania

IJERPH, 2023, vol. 20, issue 4, 1-15

Abstract: Glyphosate, and the ever growing reliance on its use in agriculture, has been a point of contention for many years. There have been debates regarding the risk and safety of using glyphosate-based herbicides as well as the effects of occupational, accidental, or systematic. Although there have been a number of studies conducted, the biomonitoring of glyphosate poses a series of challenges. Researchers attempting to determine the occupational exposure face questions regarding the most appropriate analytical techniques and sampling procedures. The present review aims to summarize and synthetize the analytical methodologies available and suitable for the purpose of glyphosate biomonitoring studies as well as discuss the advantages and disadvantages of each analytical technique, from the most modern to more well-established and older ones. The most relevant publications that have described analytical methods and published within the last 12 years were studied. Methods were compared, and the advantages and disadvantages of each methods were discussed. A total of 35 manuscripts describing analytical methods for glyphosate determination were summarized and discussed, with the most relevant one being compared. For methods that were not intended for biological samples, we discussed if they could be used for biomonitoring and approaches to adapt these methods for this purpose.

Keywords: glyphosate; exposure; biomonitoring; bioanalytical methods (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2023
References: View references in EconPapers View complete reference list from CitEc
Citations: View citations in EconPapers (1)

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