Clinical Characteristics and Predictors of Long-Term Prognosis of Acute Peripheral Arterial Ischemia Patients Treated Surgically

Piotr Myrcha (), Mariusz Kozak, Jakub Myrcha, Mirosław Ząbek, João Rocha-Neves, Jerzy Głowiński, Włodzimierz Hendiger, Witold Woźniak and Izabela Taranta
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Piotr Myrcha: Department of General and Vascular Surgery, Faculty of Medicine, Medical University of Warsaw, 02-091 Warsaw, Poland
Mariusz Kozak: Department of General and Vascular Surgery, Faculty of Medicine, Medical University of Warsaw, 02-091 Warsaw, Poland
Jakub Myrcha: Department of Vascular Surgery and Angiology, Bielanski Hospital, 01-809 Warsaw, Poland
Mirosław Ząbek: Department of Neurosurgery, Centre of Postgraduate Medical Education, 01-826 Warsaw, Poland
João Rocha-Neves: Department of Angiology and Vascular Surgery, Centro Hospitalar Universitário de São João, 4200-319 Porto, Portugal
Jerzy Głowiński: Department of Vascular Surgery and Transplantalogy, Medical University of Bialystok, 15-276 Bialystok, Poland
Włodzimierz Hendiger: Department of General and Vascular Surgery, Faculty of Medicine, Medical University of Warsaw, 02-091 Warsaw, Poland
Witold Woźniak: Department of General and Vascular Surgery, Faculty of Medicine, Medical University of Warsaw, 02-091 Warsaw, Poland
Izabela Taranta: Department of General and Vascular Surgery, Faculty of Medicine, Medical University of Warsaw, 02-091 Warsaw, Poland

IJERPH, 2023, vol. 20, issue 5, 1-15

Abstract: Background: Acute peripheral arterial ischemia is a rapidly developing loss of perfusion, resulting in ischemic clinical manifestations. This study aimed to assess the incidence of cardiovascular mortality in patients with acute peripheral arterial ischemia and either atrial fibrillation (AF) or sinus rhythm (SR). Methods: This observational study involved patients with acute peripheral ischemia treated surgically. Patients were followed-up to assess cardiovascular mortality and its predictors. Results: The study group included 200 patients with acute peripheral arterial ischemia and either AF (n = 67) or SR (n = 133). No cardiovascular mortality differences between the AF and SR groups were observed. AF patients who died of cardiovascular causes had a higher prevalence of peripheral arterial disease (58.3% vs. 31.6%, p = 0.048) and hypercholesterolemia (31.2% vs. 5.3%, p = 0.028) than those who did not die of such causes. Patients with SR who died of cardiovascular causes more frequently had a GFR <60 mL/min/1.73 m 2 (47.8% vs. 25.0%, p = 0.03) and were older than those with SR who did not die of such causes. The multivariable analysis shows that hyperlipidemia reduced the risk of cardiovascular mortality in patients with AF, whereas in patients with SR, an age of ≥75 years was the predisposing factor for such mortality. Conclusions: Cardiovascular mortality of patients with acute ischemia did not differ between patients with AF and SR. Hyperlipidemia reduced the risk of cardiovascular mortality in patients with AF, whereas in patients with SR, an age of ≥75 years was a predisposing factor for such mortality.

Keywords: acute peripheral ischemia; atrial fibrillation; mortality; endovascular treatment; thrombectomy; embolectomy (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2023
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