Case Report: Acute Intoxication from Phosphine Inhalation

Longke Shi, Tianzi Jian, Yiming Tao, Yaqian Li, Guangcai Yu, Liwen Zhao, Zixin Wen, Baotian Kan () and Xiangdong Jian ()
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Longke Shi: School of Public Health, Shandong University, Jinan 250012, China
Tianzi Jian: Department of Poisoning and Occupational Diseases, Emergency Medicine, Qilu Hospital of Shandong University, Jinan 250012, China
Yiming Tao: Department of Poisoning and Occupational Diseases, Emergency Medicine, Qilu Hospital of Shandong University, Jinan 250012, China
Yaqian Li: Department of Poisoning and Occupational Diseases, Emergency Medicine, Qilu Hospital of Shandong University, Jinan 250012, China
Guangcai Yu: Department of Poisoning and Occupational Diseases, Emergency Medicine, Qilu Hospital of Shandong University, Jinan 250012, China
Liwen Zhao: School of Public Health, Shandong University, Jinan 250012, China
Zixin Wen: School of Nursing and Rehabilitation, Cheeloo College of Medicine, Shandong University, Jinan 250012, China
Baotian Kan: School of Nursing and Rehabilitation, Cheeloo College of Medicine, Shandong University, Jinan 250012, China
Xiangdong Jian: School of Public Health, Shandong University, Jinan 250012, China

IJERPH, 2023, vol. 20, issue 6, 1-7

Abstract: Aluminum phosphide is a highly effective insecticide for fumigation in granaries and is often used in rural grain storage. However, people’s awareness of its toxicity is not strong. A case of acute inhalation toxicity of phosphine caused by the use of aluminum phosphide to fumigate a granary is reported here. The case presented with aspiration pneumonia and acute left heart failure. The patient was cured using comprehensive life support treatment, including respiratory support, antiarrhythmic treatment, and blood pressure maintenance with vasoactive drugs. There is no specific antidote for phosphine poisoning at present, and the comprehensive application of restricted fluid resuscitation, high-dose glucocorticoid shock, vasoactive drugs and bedside hemofiltration is significant in improving the prognosis of patients. It is also important to remind people to pay attention to their own protection in the process of using aluminum phosphide.

Keywords: phosphine; poisoning; inhalation; cardiac toxicity case report (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2023
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