Biomonitoring California Protocol for Following up on Elevated Levels of Urinary Arsenic

Shoba Iyer, Duyen Kauffman (), Craig Steinmaus and Sara Hoover
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Shoba Iyer: Office of Environmental Health Hazard Assessment (OEHHA), Oakland, CA 94612, USA
Duyen Kauffman: California Department of Public Health (CDPH), Richmond, CA 94804, USA
Craig Steinmaus: Office of Environmental Health Hazard Assessment (OEHHA), Oakland, CA 94612, USA
Sara Hoover: Office of Environmental Health Hazard Assessment (OEHHA), Oakland, CA 94612, USA

IJERPH, 2023, vol. 20, issue 7, 1-11

Abstract: Objectives: to develop and implement a follow-up protocol for Biomonitoring California study participants with elevated levels of urinary arsenic, particularly inorganic forms. Methods: We selected 20 μg/L as the level of concern for urinary inorganic arsenic; samples with total arsenic ≥20 μg/L were speciated. Participants with elevated inorganic arsenic were notified of their level and invited to participate in a telephone survey to help determine possible exposure sources. We illustrate the protocol in four Biomonitoring California studies, which collected samples from 2010–2013 in locations across the state. Results: 48 participants in the four studies had elevated urinary inorganic arsenic levels. Consumption of rice and rice-based products was the most commonly identified potential source of inorganic arsenic exposure. Conclusions: Of 48 participants with elevated inorganic arsenic, 27 would have been missed if we had used the previously published threshold of 50 µg/L total arsenic to identify urine samples for speciation. This protocol fills a gap in the clinical literature by providing a more health-protective approach to identify individuals with elevated urinary inorganic arsenic and help determine potentially significant exposure sources.

Keywords: biomonitoring; arsenic (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2023
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