Changes in Skeletal Muscle Troponin T and Vitamin D Binding Protein (DBP) Concentrations in the Blood of Male Amateur Athletes Participating in a Marathon and 100 km Adventure Race

Jacek Borkowski (), Tadeusz Stefaniak and Piotr Cych
Additional contact information
Jacek Borkowski: Department of Physiology and Biochemistry, Wroclaw University of Health and Sport Sciences, 35 J.I. Paderewski Avenue, 51-612 Wroclaw, Poland
Tadeusz Stefaniak: Department of Immunology, Pathophysiology and Veterinary Preventive Medicine, Wrocław University of Environmental and Life Sciences, C.K. Norwida 31 Str, 50-375 Wrocław, Poland
Piotr Cych: Department of Sport Didactics, Wroclaw University of Health and Sport Sciences, 35 J.I. Paderewski Avenue, 51-612 Wroclaw, Poland

IJERPH, 2023, vol. 20, issue 9, 1-10

Abstract: This study assessed changes in creatine kinase (CK) activity and skeletal muscle troponin T (sTnT) concentrations in the blood, to estimate the degree of muscle degradation after exercise. In addition, the concentration of vitamin D binding protein (DBP) in the blood was assessed. DBP concentrations were measured in blood as a marker for plasma load by monomeric actin. The study included marathon (MR) participants and 100 km adventure race (AR) participants, who were examined before and after the race. There was a significant (16-fold) increase in CK activity among AR participants, and a significant increase in sTnT concentration―127% in the MR group and 113% in the AR group, while there was a statistically significant decrease in DBP concentration by 14% in the AR group. In addition, it was observed that the initial concentration of DBP in both groups was in a normal range, but was lower than the average population, and the DBP concentration in the AR group was lower than in the MR group. It was concluded that exhausting physical effort such as a marathon or adventure races causes muscle damage with a far stronger influence on sarcoplasm than on filaments. The short-term and slight reduction in the concentration of DBP in blood after such efforts may be due to the appearance of monomeric actin in plasma.

Keywords: skeletal troponin T; vitamin D-binding protein; globulin Gc; marathon run; adventure race; muscle injury (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2023
References: View references in EconPapers View complete reference list from CitEc
Citations:

Downloads: (external link)
https://www.mdpi.com/1660-4601/20/9/5692/pdf (application/pdf)
https://www.mdpi.com/1660-4601/20/9/5692/ (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:gam:jijerp:v:20:y:2023:i:9:p:5692-:d:1137794

Access Statistics for this article

IJERPH is currently edited by Ms. Jenna Liu

More articles in IJERPH from MDPI
Bibliographic data for series maintained by MDPI Indexing Manager ().