Heart Rate Variability in Relation to Cardiovascular Autonomic Neuropathy Among Patients at an Urban Hospital in Kazakhstan

Nazira Bekenova, Tamara Vochshenkova (), Alisher Aitkaliyev, Balkenzhe Imankulova, Zhanatgul Turgumbayeva, Balzhan Kassiyeva and Valeriy Benberin
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Nazira Bekenova: Medical Centre Hospital of President’s Affairs Administration of the Republic of Kazakhstan, Mangilik El 80, Astana 010000, Kazakhstan
Tamara Vochshenkova: Medical Centre Hospital of President’s Affairs Administration of the Republic of Kazakhstan, Mangilik El 80, Astana 010000, Kazakhstan
Alisher Aitkaliyev: Medical Centre Hospital of President’s Affairs Administration of the Republic of Kazakhstan, Mangilik El 80, Astana 010000, Kazakhstan
Balkenzhe Imankulova: University Medical Center Corporate Fund, Kerey and Zhanibek Khans St 5/1, Astana 010000, Kazakhstan
Zhanatgul Turgumbayeva: Medical Centre Hospital of President’s Affairs Administration of the Republic of Kazakhstan, Mangilik El 80, Astana 010000, Kazakhstan
Balzhan Kassiyeva: Medical Centre Hospital of President’s Affairs Administration of the Republic of Kazakhstan, Mangilik El 80, Astana 010000, Kazakhstan
Valeriy Benberin: Medical Centre Hospital of President’s Affairs Administration of the Republic of Kazakhstan, Mangilik El 80, Astana 010000, Kazakhstan

IJERPH, 2024, vol. 21, issue 12, 1-10

Abstract: In clinical practice, heart rate variability (HRV) has not been considered an indicator for the preventive assessment of cardiovascular autonomic neuropathy (CAN). The paper studies HRV in a large, randomly selected group. A cross-sectional study included a representative sample of 5707 Kazakhs aged 20 years and older from a total population of 25,454 attached to an urban clinic in the capital of Kazakhstan. The sample was drawn from individuals who visited the clinic for a preventive examination. CAN diagnosis was confirmed using data from questionnaires, electronic medical records, HRV, and heart rate measurements. Mean values of the standard deviation of normal sinus RR intervals (SDNN) and the root mean square of successive RR interval differences (RMSSDs) from a 24 h electrocardiogram recording were assessed. CAN was identified in 17.19% of the study participants, with a ratio of the subclinical to clinical phase of 1:0.24. Diabetes mellitus was present in 30.99% of patients with CAN. The prevalence of CAN varied by sex and age, aligning with the prevalence trajectory of diabetes. It was concluded that the SDNN and RMSSD parameters in electrocardiographic studies can be used for preventive measures in the context of limited healthcare resources.

Keywords: cardiovascular autonomic neuropathy; cardiovascular diseases; heart rate variability; autonomic nervous system (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2024
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