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The Risk of the Aggravation of Diabetic Foot According to Air Quality Factors in the Republic of Korea: A Nationwide Population-Based Study

Saintpee Kim, Sungho Won and Young Yi ()
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Saintpee Kim: Department of Orthopedic Surgery, Gangbuk Etteum Hospital, Seoul 01170, Republic of Korea
Sungho Won: RexSoft Corps, Seoul 08826, Republic of Korea
Young Yi: Department of Orthopedic Surgery Foot and Ankle Service, Inje University Paik Central Hospital, Seoul 04551, Republic of Korea

IJERPH, 2024, vol. 21, issue 6, 1-15

Abstract: This study aims to examine the association between the occurrence of diabetic foot and air quality (SO 2 , CO, NO 2 , O 3 ). Open data were collected to conduct a big data study. Patient information was gathered from the National Health Insurance Service, and the National Institute of Environmental Science’s air quality data were used. A total study population of 347,543 cases were reviewed (case = 13,353, control = 334,190). The lag period from air quality changes to the actual amputation operation was calculated for each factor. The frequency of diabetic foot amputation in each region was identified and analyzed using a distributed lag non-linear model. Gangwon-do showed the highest relative risks (RRs) for SO 2 and CO, while Chungcheongnam-do exhibited the highest RR for NO 2 . Jeju had the highest RR for O 3 . Regions like Incheon, Busan, and the capital region also showed significant risk increases. These findings emphasize the importance of tailored air quality management to address diabetic foot complications effectively.

Keywords: diabetic foot; lower extremity amputation; air quality; diabetic vasculopathy; diabetic neuropathy (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2024
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