Inflammatory Status in Trained and Untrained Mice at Different Pollution Levels

Roberta Foster, Mariana Matera Veras, Andre Luis Lacerda Bachi (), Jonatas Bussador do Amaral, Victor Yuji Yariwake, Dunia Waked, Ana Clara Bastos Rodrigues, Marilia Farrajota, Robério Pereira Pires, Karina Pantaleão, Juliana de Melo Batista dos Santos, Francys Helen Damian, Paulo Hilário Saldiva and Mauro Walter Vaisberg
Additional contact information
Roberta Foster: Department of Otorhinolaryngology and Head and Neck Surgery, Escola Paulista de Medicina, Federal University of São Paulo, São Paulo 04021-001, Brazil
Mariana Matera Veras: Experimental Atmospheric Pollution Laboratory, School of Medicine, University of São Paulo, São Paulo 01246-903, Brazil
Andre Luis Lacerda Bachi: Post-Graduation Program in Health Science, University of Santo Amaro, São Paulo 04743-030, Brazil
Jonatas Bussador do Amaral: Department of Otorhinolaryngology and Head and Neck Surgery, Escola Paulista de Medicina, Federal University of São Paulo, São Paulo 04021-001, Brazil
Victor Yuji Yariwake: Experimental Atmospheric Pollution Laboratory, School of Medicine, University of São Paulo, São Paulo 01246-903, Brazil
Dunia Waked: Experimental Atmospheric Pollution Laboratory, School of Medicine, University of São Paulo, São Paulo 01246-903, Brazil
Ana Clara Bastos Rodrigues: Experimental Atmospheric Pollution Laboratory, School of Medicine, University of São Paulo, São Paulo 01246-903, Brazil
Marilia Farrajota: Department of Otorhinolaryngology and Head and Neck Surgery, Escola Paulista de Medicina, Federal University of São Paulo, São Paulo 04021-001, Brazil
Robério Pereira Pires: Department of Otorhinolaryngology and Head and Neck Surgery, Escola Paulista de Medicina, Federal University of São Paulo, São Paulo 04021-001, Brazil
Karina Pantaleão: Department of Otorhinolaryngology and Head and Neck Surgery, Escola Paulista de Medicina, Federal University of São Paulo, São Paulo 04021-001, Brazil
Juliana de Melo Batista dos Santos: Department of Physical Therapy, School of Medicine, University of São Paulo, São Paulo 01246-903, Brazil
Francys Helen Damian: Department of Otorhinolaryngology and Head and Neck Surgery, Escola Paulista de Medicina, Federal University of São Paulo, São Paulo 04021-001, Brazil
Paulo Hilário Saldiva: Experimental Atmospheric Pollution Laboratory, School of Medicine, University of São Paulo, São Paulo 01246-903, Brazil
Mauro Walter Vaisberg: Department of Otorhinolaryngology and Head and Neck Surgery, Escola Paulista de Medicina, Federal University of São Paulo, São Paulo 04021-001, Brazil

IJERPH, 2024, vol. 21, issue 7, 1-14

Abstract: Atmospheric pollution can be defined as a set of changes that occur in the composition of the air, making it unsuitable and/or harmful and thereby generating adverse effects on human health. The regular practice of physical exercise (PE) is associated with the preservation and/or improvement of health; however, it can be influenced by neuroimmunoendocrine mechanisms and external factors such as air pollution, highlighting the need for studies involving the practice of PE in polluted environments. Herein, 24 male C57BL/6 mice were evaluated, distributed into four groups (exposed to a high concentration of pollutants/sedentary, exposed to a high concentration of pollutants/exercised, exposed to ambient air/sedentary, and exposed to ambient air/exercised). The exposure to pollutants occurred in the environmental particle concentrator (CPA) and the physical training was performed on a treadmill specially designed for use within the CPA. Pro- and anti-inflammatory markers in blood and bronchoalveolar lavage (BALF), BALF cellularity, and lung tissue were evaluated. Although the active group exposed to a high concentration of pollution showed a greater inflammatory response, both the correlation analysis and the ratio between pro- and anti-inflammatory cytokines demonstrated that the exercised group presented greater anti-inflammatory activity, suggesting a protective/adaptative effect of exercise when carried out in a polluted environment.

Keywords: atmospheric pollution; physical exercise; inflammation; adaptation (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2024
References: View references in EconPapers View complete reference list from CitEc
Citations:

Downloads: (external link)
https://www.mdpi.com/1660-4601/21/7/821/pdf (application/pdf)
https://www.mdpi.com/1660-4601/21/7/821/ (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:gam:jijerp:v:21:y:2024:i:7:p:821-:d:1420653

Access Statistics for this article

IJERPH is currently edited by Ms. Jenna Liu

More articles in IJERPH from MDPI
Bibliographic data for series maintained by MDPI Indexing Manager ().