Internet-Based Psycho-Physical Exercise Intervention Program in Mild-to-Moderate Depression: The Study Protocol of the SONRIE Randomized Controlled Trial

Juan Manuel Escudier-Vázquez, Manuel Ruiz-Muñoz, Inmaculada Garrido-Palomino, Sonia Ortega-Gómez, Eulalio Juan Valmisa Gómez de Lara, María del Mar Espinosa Nogales, Alicia Viglerio Montero, Miguel Ángel Rosety-Rodríguez, David Jiménez-Pavón, Ana Carbonell-Baeza and Vanesa España-Romero ()
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Juan Manuel Escudier-Vázquez: MOVE-IT Research Group, Department of Physical Education, Faculty of Education Sciences, University of Cadiz, 11519 Cadiz, Spain
Manuel Ruiz-Muñoz: MOVE-IT Research Group, Department of Physical Education, Faculty of Education Sciences, University of Cadiz, 11519 Cadiz, Spain
Inmaculada Garrido-Palomino: MOVE-IT Research Group, Department of Physical Education, Faculty of Education Sciences, University of Cadiz, 11519 Cadiz, Spain
Sonia Ortega-Gómez: MOVE-IT Research Group, Department of Physical Education, Faculty of Education Sciences, University of Cadiz, 11519 Cadiz, Spain
Eulalio Juan Valmisa Gómez de Lara: Mental Health Service, Puerto Real University Hospital, 11510 Cadiz, Spain
María del Mar Espinosa Nogales: Mental Health Service, Puerto Real University Hospital, 11510 Cadiz, Spain
Alicia Viglerio Montero: Mental Health Service, Puerto Real University Hospital, 11510 Cadiz, Spain
Miguel Ángel Rosety-Rodríguez: MOVE-IT Research Group, Department of Physical Education, Faculty of Education Sciences, University of Cadiz, 11519 Cadiz, Spain
David Jiménez-Pavón: MOVE-IT Research Group, Department of Physical Education, Faculty of Education Sciences, University of Cadiz, 11519 Cadiz, Spain
Ana Carbonell-Baeza: MOVE-IT Research Group, Department of Physical Education, Faculty of Education Sciences, University of Cadiz, 11519 Cadiz, Spain
Vanesa España-Romero: MOVE-IT Research Group, Department of Physical Education, Faculty of Education Sciences, University of Cadiz, 11519 Cadiz, Spain

IJERPH, 2025, vol. 22, issue 4, 1-21

Abstract: The COVID-19 pandemic has intensified depression due to isolation and reduced physical activity, highlighting the need for accessible remote treatments. The SONRIE study evaluates the effectiveness of a 12-week online intervention combining physical exercise and internet-based cognitive–behavioral therapy on depressive symptoms in adults with mild-to-moderate depression. This randomized controlled trial involved 80 adults aged 25–65 years diagnosed with depression according to the ICD-10 criteria. Participants were randomized to an experimental group receiving the combined online intervention or to a control group receiving standard care. The primary outcome was the change in depression severity, assessed by the Beck Depression Inventory, with outcomes measured at baseline, immediately post-intervention, and after an 8-week follow-up phase. Statistical analyses include analysis of covariance to compare group changes over time, with effect sizes quantifying the intervention’s impact. The SONRIE study demonstrates a promising online approach for treating depression, with potential implications for clinical practice and public health strategies.

Keywords: depression; mental health; internet-based cognitive–behavioral therapy; physical exercise; endocannabinoid system; randomized controlled trial (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2025
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