Exposure of Laboratory Mice to Domestic Cooking Gas: - Implications for Toxicity

Oyeronke A. Odunola, Emmanuel Uka, Kazeem A. Akinwumi, Michael A. Gbadegesin, Olabode O. Osifeso and Madu D. Ibegbu
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Oyeronke A. Odunola: Cancer Research and Molecular Biology Laboratories, Department of Biochemistry, College of Medicine, University of Ibadan, Ibadan, Nigeria
Emmanuel Uka: Cancer Research and Molecular Biology Laboratories, Department of Biochemistry, College of Medicine, University of Ibadan, Ibadan, Nigeria
Kazeem A. Akinwumi: Cancer Research and Molecular Biology Laboratories, Department of Biochemistry, College of Medicine, University of Ibadan, Ibadan, Nigeria
Michael A. Gbadegesin: Cancer Research and Molecular Biology Laboratories, Department of Biochemistry, College of Medicine, University of Ibadan, Ibadan, Nigeria
Olabode O. Osifeso: Cancer Research and Molecular Biology Laboratories, Department of Biochemistry, College of Medicine, University of Ibadan, Ibadan, Nigeria
Madu D. Ibegbu: Cancer Research and Molecular Biology Laboratories, Department of Biochemistry, College of Medicine, University of Ibadan, Ibadan, Nigeria

IJERPH, 2008, vol. 5, issue 3, 1-5

Abstract: The ability of domestic cooking gas to induce hepatotoxicity and clastogenicity in mice was studied. The mice were exposed to domestic gas for twenty-one days at doses of 100 mg/kg, 200 mg/kg and 300 mg/kg respectively. The positive control group of mice were given sodium arsenite intraperitoneously at a dose of 2.5mg/kg body weight. While the negative control group had only distilled water, sodium arsenite significantly (p

Keywords: Domestic cooking gas; sodium arsenite; micronucleated polychromatic erythrocyte; ?-GT and AP; mice (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2008
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