Genotoxicity in child populations exposed to Polycyclic Aromatic Hydrocarbons (PAHs) in the air from Tabasco, Mexico

Rodríguez T. Gamboa, Aldeco R. Gamboa, Alvarez H. Bravo and Wegman P. Ostrosky
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Rodríguez T. Gamboa: División Académica de Ciencias Básicas, Universidad Juárez Autónoma de Tabasco. Km 0.5 carretera Cunduacán-Jalpa de Méndez, Tabasco, México
Aldeco R. Gamboa: División Académica de Ciencias Biológicas, Universidad Juárez Autónoma de Tabasco. Km 0.5 carretera Villahermosa- Cárdenas, Tabasco, México
Alvarez H. Bravo: Centro de Ciencias de la Atmósfera, Universidad Nacional Autónoma de México, Circuito Exterior, Ciudad Universitaria, México, D.F.
Wegman P. Ostrosky: Laboratorio de Genómica, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Circuito Exterior, Ciudad Universitaria, México, D.F.

IJERPH, 2008, vol. 5, issue 5, 1-7

Abstract: The economy of the state of Tabasco is based on oil extraction. However, this imposes major effects to the environment and communities. Examples are the Polycyclic Aromatic Hydrocarbons (PAHs) that may be found in the soil, water and sediment of the region. Their volatility makes them available to living beings and results in genotoxic activity. The purpose of this study was to quantify the levels of PAHs in the air at several points in the state, and to analyze their relationship with possible damage to DNA on local inhabitants. Single Cell Gel Electrophoresis Assay (Comet Assay) was applied to peripheral blood lymphocytes of five groups of children between six and 15 years of age. PAH samples were analyzed following US/EPA TO-13-A method. Results indicated the presence in the air of most of the 16 PAHs considered as high priority by EPA, some of which have been reported with carcinogenic activity. Differences (p

Keywords: Genotoxicity; polycyclic hydrocarbons; comet assay; single cell gel electrophoresis; PAHs (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2008
References: View complete reference list from CitEc
Citations: View citations in EconPapers (3)

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