Epidemiological Study of Rickettsial Infections in Patients with Hypertransaminemia in Madrid (Spain)

Lourdes Lledó, Rosario González, María Isabel Gegúndez, María Beltrán and José Vicente Saz
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Lourdes Lledó: Department of Microbiology and Parasitology, Faculty of Medicine, University of Alcalá, Ctra. Madrid-Barcelona Km 33.6, Alcalá de Henares 28871, Spain
Rosario González: Department of Microbiology and Parasitology, Faculty of Medicine, University of Alcalá, Ctra. Madrid-Barcelona Km 33.6, Alcalá de Henares 28871, Spain
María Isabel Gegúndez: Department of Microbiology and Parasitology, Faculty of Medicine, University of Alcalá, Ctra. Madrid-Barcelona Km 33.6, Alcalá de Henares 28871, Spain
María Beltrán: Department of Microbiology and Parasitology, Faculty of Medicine, University of Alcalá, Ctra. Madrid-Barcelona Km 33.6, Alcalá de Henares 28871, Spain
José Vicente Saz: Department of Microbiology and Parasitology, Faculty of Medicine, University of Alcalá, Ctra. Madrid-Barcelona Km 33.6, Alcalá de Henares 28871, Spain

IJERPH, 2009, vol. 6, issue 10, 1-8

Abstract: A retrospective analysis was performed to detect anti-rickettsial antibodies in the serum of patients with hypertransaminemia of unknown etiology, and in that of healthy members of the general population of Madrid (Spain). Among 143 patients 16 (11.2%) were positive for anti- R. conorii IgG antibodies and 7% for R. typhi . PCR analysis was performed in patients with IgM antibodies. Among 143 healthy subjects from the general population, seven (4.9%) were positive for anti- R. conorii IgG antibodies, and 2.8% for R. typhi . These results show that anti-rickettsial antibodies are more commonly detected in patients with hypertransaminemia than in healthy people.

Keywords: Rickettsiae; hypertransaminemia; liver dysfunction; prevalence; Spain (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2009
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