Real World Study to Evaluate the Effectiveness of Varenicline and Cognitive-Behavioural Interventions for Smoking Cessation

Josep Mª. Ramon and Eugeni Bruguera
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Josep Mª. Ramon: Smoking Cessation Clinic. Hospital Universitario de Bellvitge. Feixa Llarga s/n 08907 Hospitalet. Barcelona, Spain
Eugeni Bruguera: Smoking Cessation Clinic. Hospital Universitario de Vall d’Hebron. Passeig de la Vall d’Hebron 119-129. 08035 Barcelona, Spain

IJERPH, 2009, vol. 6, issue 4, 1-9

Abstract: A prospective pragmatic interventional study was conducted to evaluate the effectiveness of varenicline for smoking cessation among a cohort of motivated smokers attending two smoking cessation clinics. Smokers between 18 and 65 years who had smoked 10 or more cigarettes per day were included. All participants received cognitive-behavioural varenicline according to approved dose and prescriptions. Continuous abstinence, validated by exhaled CO levels, was assessed in each control. A total of 264 smokers – 155 males (58.7%) and 109 females (41.3%) – were included. Mean age was 43.7, amount smoked was 23 cigarettes per day and 61.4% had at least one prior attempt to quit. The continuous abstinence rate at end of treatment (12 wks) was 58.3%. Conclusions: varenicline and cognitive-behavioural intervention are effective for smoking cessation with high continuous abstinence rates when are used in a clinical setting.

Keywords: Smoking cessation; varenicline; cognitive-behavioural intervention; continuous abstinence (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2009
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