Alcohol Consumption and Development of Acute Respiratory Distress Syndrome: A Population-Based Study

Lokendra Thakur, Marija Kojicic, Sweta J. Thakur, Matthew S. Pieper, Rahul Kashyap, Cesar A. Trillo-Alvarez, Fernandez Javier, Rodrigo Cartin-Ceba and Ognjen Gajic
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Lokendra Thakur: Division of Pulmonary and Critical Care Medicine, College of Medicine, Mayo Clinic, Rochester, MN; (M.E.T.R.I.C.) Multidisciplinary Epidemiology and Translational Research in Intensive Care, 200 1st St SW, Rochester, MN 55905, USA
Marija Kojicic: Division of Pulmonary and Critical Care Medicine, College of Medicine, Mayo Clinic, Rochester, MN; (M.E.T.R.I.C.) Multidisciplinary Epidemiology and Translational Research in Intensive Care, 200 1st St SW, Rochester, MN 55905, USA
Sweta J. Thakur: Division of Pulmonary and Critical Care Medicine, College of Medicine, Mayo Clinic, Rochester, MN; (M.E.T.R.I.C.) Multidisciplinary Epidemiology and Translational Research in Intensive Care, 200 1st St SW, Rochester, MN 55905, USA
Matthew S. Pieper: Division of Pulmonary and Critical Care Medicine, College of Medicine, Mayo Clinic, Rochester, MN; (M.E.T.R.I.C.) Multidisciplinary Epidemiology and Translational Research in Intensive Care, 200 1st St SW, Rochester, MN 55905, USA
Rahul Kashyap: Division of Pulmonary and Critical Care Medicine, College of Medicine, Mayo Clinic, Rochester, MN; (M.E.T.R.I.C.) Multidisciplinary Epidemiology and Translational Research in Intensive Care, 200 1st St SW, Rochester, MN 55905, USA
Cesar A. Trillo-Alvarez: Division of Pulmonary and Critical Care Medicine, College of Medicine, Mayo Clinic, Rochester, MN; (M.E.T.R.I.C.) Multidisciplinary Epidemiology and Translational Research in Intensive Care, 200 1st St SW, Rochester, MN 55905, USA
Fernandez Javier: Division of Pulmonary and Critical Care Medicine, College of Medicine, Mayo Clinic, Rochester, MN; (M.E.T.R.I.C.) Multidisciplinary Epidemiology and Translational Research in Intensive Care, 200 1st St SW, Rochester, MN 55905, USA
Rodrigo Cartin-Ceba: Division of Pulmonary and Critical Care Medicine, College of Medicine, Mayo Clinic, Rochester, MN; (M.E.T.R.I.C.) Multidisciplinary Epidemiology and Translational Research in Intensive Care, 200 1st St SW, Rochester, MN 55905, USA
Ognjen Gajic: Division of Pulmonary and Critical Care Medicine, College of Medicine, Mayo Clinic, Rochester, MN; (M.E.T.R.I.C.) Multidisciplinary Epidemiology and Translational Research in Intensive Care, 200 1st St SW, Rochester, MN 55905, USA

IJERPH, 2009, vol. 6, issue 9, 1-10

Abstract: This retrospective population-based study evaluated the effects of alcohol consumption on the development of acute respiratory distress syndrome (ARDS). Alcohol consumption was quantified based on patient and/or family provided information at the time of hospital admission. ARDS was defined according to American-European consensus conference (AECC). From 1,422 critically ill Olmsted county residents, 1,357 had information about alcohol use in their medical records, 77 (6%) of whom developed ARDS. A history of significant alcohol consumption (more than two drinks per day) was reported in 97 (7%) of patients. When adjusted for underlying ARDS risk factors (aspiration, chemotherapy, high-risk surgery, pancreatitis, sepsis, shock), smoking, cirrhosis and gender, history of significant alcohol consumption was associated with increased risk of ARDS development (odds ratio 2.9, 95% CI 1.3–6.2). This population-based study confirmed that excessive alcohol consumption is associated with higher risk of ARDS.

Keywords: alcohol; ARDS; population (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2009
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