Endocrine Disruptors and Obesity: An Examination of Selected Persistent Organic Pollutants in the NHANES 1999–2002 Data

Mai A. Elobeid, Miguel A. Padilla, David W. Brock, Douglas M. Ruden and David B. Allison
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Mai A. Elobeid: Department of Biostatistics, University of Alabama at Birmingham, 1665 University Boulevard, Birmingham, AL, 35294, USA
Miguel A. Padilla: Department of Psychology, Old Dominion University, 250 Mills Godwin Building, Norfolk, VA 23529, USA
David W. Brock: Division of Cardiovascular Disease, Department of Medicine, University of Alabama at Birmingham, 1665 University Boulevard, Birmingham, AL 35294, USA
Douglas M. Ruden: Institute of Environmental Health Sciences, Wayne State University, 259 Mack Avenue, Detroit, MI 48201, USA
David B. Allison: Department of Biostatistics, University of Alabama at Birmingham, 1665 University Boulevard, Birmingham, AL, 35294, USA

IJERPH, 2010, vol. 7, issue 7, 1-18

Abstract: Recent evidence suggests that endocrine disrupting chemicals (EDCs) may cause perturbations in endogenous hormonal regulation that predispose to weight gain. Using data from NHANES (1999–2002), we investigated the association between body mass index (BMI), waist circumference (WC) and selected persistent organic pollutants (POPs) via multiple linear regressions. Consistent interaction was found between gender, ln oxychlordane and ln p,p’ DDT. Also, we found an association between WC and ln oxychlordane and ln hpcdd in subjects with detectable levels of POPs, whereas an association between WC and ln p,p’ DDT was observed in all subjects. Furthermore, ln Ocdd showed an increase with higher WC and BMI, whereas, ln trans-nonachlor decreased with higher BMI. Hence, BMI and WC are associated with POPs levels, making the chemicals plausible contributors to the obesity epidemic.

Keywords: Obesity; endocrine disruptors; waist circumference; persistent organic pollutants; public health (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2010
References: View complete reference list from CitEc
Citations: View citations in EconPapers (2)

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