Related Factors of Insulin Resistance in Korean Children: Adiposity and Maternal Insulin Resistance

Young-Gyu Cho, Jae-Heon Kang, Yang-Im Hur, Jihyun Song and Kang-Sook Lee
Additional contact information
Young-Gyu Cho: Department of Family Medicine, Seoul-Paik Hospital, College of Medicine, Inje University, 85 Jeo-dong 2-ga, Jung-gu, Seoul 100032, Korea
Jae-Heon Kang: Department of Family Medicine, Seoul-Paik Hospital, College of Medicine, Inje University, 85 Jeo-dong 2-ga, Jung-gu, Seoul 100032, Korea
Yang-Im Hur: Department of Family Medicine, Seoul-Paik Hospital, College of Medicine, Inje University, 85 Jeo-dong 2-ga, Jung-gu, Seoul 100032, Korea
Jihyun Song: Division of Metabolic Diseases, Center for Biomedical Sciences, National Institute of Health, 187 Osongsaengmyeong 2-ro, Gangoe-myeon, Cheongwon-gun, Chungcheongbuk-do 363951, Korea
Kang-Sook Lee: Department of Preventive Medicine, College of Medicine, The Catholic University of Korea, Banpo-dong, Seocho-gu, Seoul 137-701, Korea

IJERPH, 2011, vol. 8, issue 12, 1-12

Abstract: Increased adiposity and unhealthy lifestyle augment the risk for type 2 diabetes in children with familial predisposition. Insulin resistance (IR) is an excellent clinical marker for identifying children at high risk for type 2 diabetes. This study was conducted to investigate parental, physiological, behavioral and socio-economic factors related to IR in Korean children. This study is a cross-sectional study using data from 111 children aged 7 years and their parents. Homeostasis model assessment of insulin resistance (HOMA-IR) was calculated using fasting glucose and insulin level as a marker of IR. All children’s adiposity indices ( r = 0.309–0.318, all P -value = 0.001) and maternal levels of fasting insulin ( r = 0.285, P -value = 0.003) and HOMA-IR ( r = 0.290, P -value = 0.002) were positively correlated with children’s HOMA-IR level. There was no statistical difference of children’s HOMA-IR level according to children’s lifestyle habits and socioeconomic status of families. An increase of 1 percentage point in body fat was related to 2.7% increase in children’s HOMA-IR ( P -value P -value = 0.002). This study shows that children’s adiposity and maternal IR are positively associated with children’s IR.

Keywords: insulin resistance; child; parent; adiposity; lifestyle habit (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2011
References: View complete reference list from CitEc
Citations:

Downloads: (external link)
https://www.mdpi.com/1660-4601/8/12/4596/pdf (application/pdf)
https://www.mdpi.com/1660-4601/8/12/4596/ (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:gam:jijerp:v:8:y:2011:i:12:p:4596-4607:d:15182

Access Statistics for this article

IJERPH is currently edited by Ms. Jenna Liu

More articles in IJERPH from MDPI
Bibliographic data for series maintained by MDPI Indexing Manager ().