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Differential Effects of High-Carbohydrate and High-Fat Diet Composition on Metabolic Control and Insulin Resistance in Normal Rats

Jorge L. Ble-Castillo, María A. Aparicio-Trapala, Isela E. Juárez-Rojop, Jorge E. Torres-Lopez, Jose D. Mendez, Hidemi Aguilar-Mariscal, Viridiana Olvera-Hernández, Leydi C. Palma-Cordova and Juan C. Diaz-Zagoya
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Jorge L. Ble-Castillo: Centro de Investigación, DACS, Universidad Juarez Autónoma de Tabasco (UJAT), Villahermosa, Tabasco 86150, Mexico
María A. Aparicio-Trapala: División Académica de Ciencias Agropecuarias, UJAT, Villahermosa, Tabasco 86280, Mexico
Isela E. Juárez-Rojop: Centro de Investigación, DACS, Universidad Juarez Autónoma de Tabasco (UJAT), Villahermosa, Tabasco 86150, Mexico
Jorge E. Torres-Lopez: Centro de Investigación, DACS, Universidad Juarez Autónoma de Tabasco (UJAT), Villahermosa, Tabasco 86150, Mexico
Jose D. Mendez: Unidad de Investigación Médica en Enfermedades Metabólicas, Hospital de Especialidades, CMN, Siglo XXI, IMSS, Mexico D.F. 06703, Mexico
Hidemi Aguilar-Mariscal: Centro de Investigación, DACS, Universidad Juarez Autónoma de Tabasco (UJAT), Villahermosa, Tabasco 86150, Mexico
Viridiana Olvera-Hernández: Centro de Investigación, DACS, Universidad Juarez Autónoma de Tabasco (UJAT), Villahermosa, Tabasco 86150, Mexico
Leydi C. Palma-Cordova: Centro de Investigación, DACS, Universidad Juarez Autónoma de Tabasco (UJAT), Villahermosa, Tabasco 86150, Mexico
Juan C. Diaz-Zagoya: Centro de Investigación, DACS, Universidad Juarez Autónoma de Tabasco (UJAT), Villahermosa, Tabasco 86150, Mexico

IJERPH, 2012, vol. 9, issue 5, 1-14

Abstract: The macronutrient component of diets is critical for metabolic control and insulin action. The aim of this study was to compare the effects of high fat diets (HFDs) vs. high carbohydrate diets (HCDs) on metabolic control and insulin resistance in Wistar rats. Thirty animals divided into five groups (n = 6) were fed: (1) Control diet (CD); (2) High-saturated fat diet (HSFD); (3) High-unsaturated fat diet (HUFD); (4) High-digestible starch diet, (HDSD); and (5) High-resistant starch diet (HRSD) during eight weeks. HFDs and HCDs reduced weight gain in comparison with CD, however no statistical significance was reached. Calorie intake was similar in both HFDs and CD, but rats receiving HCDs showed higher calorie consumption than other groups, ( p

Keywords: metabolic control; high-carbohydrate diet; high-fat diet; resistant starch; insulin resistance (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2012
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