Inflammation and Peripheral Arterial Disease

Salvatore Santo Signorelli, Elisa Marino and Salvatore Scuto
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Salvatore Santo Signorelli: Department of Clinical and Experimental Medicine School of Medicine, University of Catania, 95122 Catania, Italy
Elisa Marino: Department of Clinical and Experimental Medicine School of Medicine, University of Catania, 95122 Catania, Italy
Salvatore Scuto: Department of Clinical and Experimental Medicine School of Medicine, University of Catania, 95122 Catania, Italy

J, 2019, vol. 2, issue 2, 1-10

Abstract: Peripheral arterial disease (PAD) is an atherosclerotic disease closely associated with high morbidity and mortality in cardiac events. Inflammation is crucial in atherosclerosis both at triggering and in progression. Numerous inflammatory biomarkers (cytokines, matrix metalloproteinases (MMPs), selectin, intracellular adhesion molecule (ICAM), vascular cell adhesion molecule (VCAM) C-reactive protein (CRP), fibrinogen) have been measured in atherosclerotic diseases including PAD. This paper summarizes the data on the inflammatory biomarkers for PAD pathophysiology and highlights the most useful markers in monitoring PAD outcomes.

Keywords: inflammation; peripheral arterial disease; biomarkers (search for similar items in EconPapers)
JEL-codes: I1 I10 I12 I13 I14 I18 I19 (search for similar items in EconPapers)
Date: 2019
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