On the Regulated Nuclear Transport of Incompletely Spliced mRNAs by HIV-Rev Protein: A Minimal Dynamic Model

Jeffrey J. Ishizuka, Delaney A. Soble, Tiffany Y. Chang and Enrique Peacock-López ()
Additional contact information
Jeffrey J. Ishizuka: Department of Chemistry, Williams College, Williamstown, MA 01267, USA
Delaney A. Soble: Department of Chemistry, Williams College, Williamstown, MA 01267, USA
Tiffany Y. Chang: Department of Chemistry, Williams College, Williamstown, MA 01267, USA
Enrique Peacock-López: Department of Chemistry, Williams College, Williamstown, MA 01267, USA

Mathematics, 2022, vol. 10, issue 21, 1-20

Abstract: A kinetic model for the HIV-1 Rev protein is developed by drawing upon mechanistic information from the literature to formulate a set of differential equations modeling the behavior of Rev and its various associated factors over time. A set of results demonstrates the possibility of oscillations in the concentration of these factors. Finally, the results are analyzed, and future directions are discussed.

Keywords: molecular regulation; autocatalysis; oscillations (search for similar items in EconPapers)
JEL-codes: C (search for similar items in EconPapers)
Date: 2022
References: View references in EconPapers View complete reference list from CitEc
Citations:

Downloads: (external link)
https://www.mdpi.com/2227-7390/10/21/3922/pdf (application/pdf)
https://www.mdpi.com/2227-7390/10/21/3922/ (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:gam:jmathe:v:10:y:2022:i:21:p:3922-:d:950333

Access Statistics for this article

Mathematics is currently edited by Ms. Emma He

More articles in Mathematics from MDPI
Bibliographic data for series maintained by MDPI Indexing Manager ().