An Optimal H-Infinity Controller for Left Ventricular Assist Devices Based on a Starling-like Controller: A Simulation Study

Mohsen Bakouri, Ahmed Alassaf, Khaled Alshareef, Saleh Abdelsalam, Husham Farouk Ismail, Ali Ganoun and Abdul-Hakeem Alomari
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Mohsen Bakouri: Department of Medical Equipment Technology, College of Applied Medical Science, Majmaah University, Al Majma’ah City 11952, Saudi Arabia
Ahmed Alassaf: Department of Medical Equipment Technology, College of Applied Medical Science, Majmaah University, Al Majma’ah City 11952, Saudi Arabia
Khaled Alshareef: Department of Medical Equipment Technology, College of Applied Medical Science, Majmaah University, Al Majma’ah City 11952, Saudi Arabia
Saleh Abdelsalam: Department of Zoology, College of Arts, Fezzan University, Traghen 71340, Libya
Husham Farouk Ismail: Department of Biomedical Equipment Technology, Inaya Medical College, Riyadh City 13541, Saudi Arabia
Ali Ganoun: Department of Electrical Engineering, College of Engineering, Tripoli University, Tripoli 22131, Libya
Abdul-Hakeem Alomari: Biomedical Engineering Department, College of Engineering, Imam Abdulrahman Bin Faisal University, Dammam 31441, Saudi Arabia

Mathematics, 2022, vol. 10, issue 5, 1-17

Abstract: Left ventricular assist devices (LVADs) are emerging innovations that provide a feasible alternative treatment for heart failure (HF) patients to enhance their quality of life. In this work, a novel physiological control system to optimize LVAD pump speed using an H-infinity controller was developed. The controller regulates the calculated target pump flow vs. measured pump flow to meet the changes in metabolic demand. The method proposes the implementation of the Frank–Starling mechanism (FSM) approach to control the speed of an LVAD using the left ventricle end-diastolic volume ( V lved ) parameter (preload). An operating point was proposed to move between different control lines within the safe area to achieve the FSM. A proportional–integral (PI) controller was used to control the gradient angle between control lines to obtain the flow target. A lumped parameter model of the cardiovascular system was used to evaluate the proposed method. Exercise and rest scenarios were assessed under multi-physiological conditions of HF patients. Simulation results demonstrated that the control system was stable and feasible under different physiological states of the cardiovascular system (CVS). In addition, the proposed controller was able to keep hemodynamic variables within an acceptable range of the mean pump flow (Qp) (max = 5.2 L/min and min = 3.2 L/min) during test conditions.

Keywords: left ventricular assist devices; heart failure; H-infinity control; physiological control; Frank–Starling mechanism (search for similar items in EconPapers)
JEL-codes: C (search for similar items in EconPapers)
Date: 2022
References: View complete reference list from CitEc
Citations: View citations in EconPapers (2)

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