Exploring Corporate Capital Structure and Overleveraging in the Pharmaceutical Industry

Samar Issa () and Hussein Issa
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Samar Issa: Department of Business Administration, Saint Peter’s University, Jersey City, NJ 07306, USA
Hussein Issa: Department of Accounting and Information Systems, Rutgers University, Piscataway, NJ 08854, USA

Risks, 2025, vol. 13, issue 2, 1-33

Abstract: This paper applies an empirical model of corporate capital structure, optimal debt, and overleveraging to estimate overleveraging measured as the difference between actual and optimal debt. Estimated using a sample of the twenty largest pharmaceutical firms, covering the time span from 2000 to 2018, the model sheds light on an industry-specific default risk. The analysis presented in this paper reveals a concerning trend in the pharmaceutical industry, with corporate excess debt steadily increasing over the past two decades, particularly peaking during the 2008 crisis and after 2013. These findings underscore the critical role of excess debt in exacerbating financial instability and highlight the pharmaceutical sector’s unique challenges, including high R&D intensity and regulatory pressures. By quantifying overleveraging and linking it to financial risk, the paper offers valuable policy implications, emphasizing the need for proactive management of optimal debt levels to mitigate default risks and enhance macroeconomic resilience.

Keywords: corporate instability; pharmaceutical sector; credit flows; financial crisis; excess debt; early warning signals (search for similar items in EconPapers)
JEL-codes: C G0 G1 G2 G3 K2 M2 M4 (search for similar items in EconPapers)
Date: 2025
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