Hydroglycerolic Solvent and Ultrasonication Pretreatment: A Green Blend for High-Efficiency Extraction of Salvia fruticosa Polyphenols

Spyros Grigorakis, Abedalghani Halahlah and Dimitris P. Makris
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Spyros Grigorakis: Department of Food Science & Nutrition, School of Environment, University of the Aegean, Mitr. Ioakim Street, 81400 Myrina, Greece
Abedalghani Halahlah: Department of Food Science & Nutrition, School of Environment, University of the Aegean, Mitr. Ioakim Street, 81400 Myrina, Greece
Dimitris P. Makris: Green Processes & Biorefinery Group, Department of Food Science & Nutrition, School of Agricultural Sciences, University of Thessaly, N. Temponera Street, 43100 Karditsa, Greece

Sustainability, 2020, vol. 12, issue 12, 1-12

Abstract: Salvia fruticosa Miller, also known as Cretan or Greek sage, is a medicinal plant with significant biological properties, which are largely ascribed to its polyphenolic composition, but there is to-date a scarcity of green and sustainable processes for efficient polyphenol extraction from this plant. The objective of this study was the implementation of an extraction process that would combine a green solvent based on glycerol, a biodiesel industry by-product, and ultrasonication pretreatment. Ultrasonication for 40 min followed by stirred-tank extraction was shown to provide significantly higher total polyphenol yield than mere stirred-tank extraction, while kinetics indicated 50 °C as the most favorable temperature, with the yield being 92 mg gallic acid equivalents (GAE) per g dry mass. Comparison of this method with a previously developed one that used methyl β -cyclodextrin revealed that the extracts obtained had similar antioxidant activity, and yield in major polyphenols including luteolin 7- O -glucuronide and rosmarinic acid was virtually equal. The current process is proposed as a sustainable and effective methodology for the generation of polyphenol-enriched extracts from S. fruticosa , which could be used as effective food antioxidants/antimicrobials and/or cosmetic constituents.

Keywords: antioxidants; extraction kinetics; glycerol; green extraction; polyphenols; Salvia fruticosa; ultrasonication (search for similar items in EconPapers)
JEL-codes: O13 Q Q0 Q2 Q3 Q5 Q56 (search for similar items in EconPapers)
Date: 2020
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