Ibuprofen and Ketoprofen—Inert Drugs or Potential Environmental Hazard?

Barbara Pawłowska (), Arkadiusz Telesiński, Marcin Sysa, Agnieszka Godela, Radomír Ščurek and Robert Biczak
Additional contact information
Barbara Pawłowska: The Faculty of Science and Technology, Jan Długosz University in Czestochowa, 13/15 Armii Krajowej Av., 42-200 Częstochowa, Poland
Arkadiusz Telesiński: The Faculty of Environmental Management and Agriculture, West Pomeranian University of Technology in Szczecin, Juliusza Słowackiego st. 17, 71-434 Szczecin, Poland
Marcin Sysa: The Faculty of Science and Technology, Jan Długosz University in Czestochowa, 13/15 Armii Krajowej Av., 42-200 Częstochowa, Poland
Agnieszka Godela: The Faculty of Science and Technology, Jan Długosz University in Czestochowa, 13/15 Armii Krajowej Av., 42-200 Częstochowa, Poland
Radomír Ščurek: Faculty of Safety Engineering, VŠB-Technical University of Ostrava, Lumirova 630/13, Vyskovice, 700 30 Ostrava, Czech Republic
Robert Biczak: The Faculty of Science and Technology, Jan Długosz University in Czestochowa, 13/15 Armii Krajowej Av., 42-200 Częstochowa, Poland

Sustainability, 2023, vol. 15, issue 2, 1-19

Abstract: Ibuprofen (IBU) and ketoprofen (KET) are among the world’s most popular and widely used nonsteroidal anti-inflammatory drugs (NSAIDs). Due to their high usage, these drugs have entered the environment, including the soil, and, like any other chemical compound, can have a negative effect on it. Therefore, an attempt was made to evaluate the effects of these two popular drugs on soil bacteria and fungi, the bivalve crustaceans ( Heterocipris incongruens) and the growth and development of spring barley. The tested drugs did not show any negative effects on the total bacterial abundance. Effects were observed on the growth and survival of H. incongruens and on the abundance of fungi in the soil at the highest concentrations tested. The presence of IBU and KET in the soil in which spring barley was cultivated caused an increase in the activity of antioxidant enzymes catalase (CAT), superoxide dismutase (SOD), and guaiacol peroxidase (POD); an increase in the content of proline and ascorbic acid (AsA) in the seedlings of this grain; and a decrease in the yield of fresh plant weight, especially at the application of concentrations of 100 and 1000 mg·kg −1 of soil’s dry weight (DW). Effects on barley seed germination potential and germination capacity, plant dry matter content, assimilation pigment content and malondialdehyde (MDA) were also observed at the highest concentrations.

Keywords: oxidative stress; H. incongruens; bacteria; fungi; spring barley (search for similar items in EconPapers)
JEL-codes: O13 Q Q0 Q2 Q3 Q5 Q56 (search for similar items in EconPapers)
Date: 2023
References: View complete reference list from CitEc
Citations:

Downloads: (external link)
https://www.mdpi.com/2071-1050/15/2/1613/pdf (application/pdf)
https://www.mdpi.com/2071-1050/15/2/1613/ (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:gam:jsusta:v:15:y:2023:i:2:p:1613-:d:1035422

Access Statistics for this article

Sustainability is currently edited by Ms. Alexandra Wu

More articles in Sustainability from MDPI
Bibliographic data for series maintained by MDPI Indexing Manager ().