A Mathematical Model on the Dynamics of In-Host Infection Cholera Disease with Vaccination

Owade Kennedy Jackob, Okaka Akinyi, Frankline Tireito and Filippo Cacace

Discrete Dynamics in Nature and Society, 2023, vol. 2023, 1-11

Abstract: In this paper, a within-host cholera mathematical model has been developed using a system of ordinary differential equations incorporating vaccine efficacy. The formulated model considers cells in an already vaccinated individual with a vaccine whose efficacy is γ. The solutions of the model have been shown to be both positive and bounded hence well-posed. The vaccine basic reproduction number has been carried out using the next generation matrix approach and is given by R0V=γ/d+μ2 and R0V 1. Furthermore, analysis of the model shows that R0V

Date: 2023
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Persistent link: https://EconPapers.repec.org/RePEc:hin:jnddns:1465228

DOI: 10.1155/2023/1465228

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