The Prevalence and Risk Factors of Gallstone Among Adults in South-East of Iran: A Population-Based Study

Alireza Ansari-Moghaddam, Alireza Khorram, Mahmodreza Miri-Bonjar, Mahdi Mohammadi and Hossein Ansari

Global Journal of Health Science, 2016, vol. 8, issue 4, 60

Abstract: OBJECTIVE- The present study aimed to evaluate the prevalence and possible risk factors of gallstone disease in the general population. PATIENTS & METHODS- This cross sectional study was carried out on a total of 1522 males and females aged ≥30 years in Zahedan district, South-East of Iran. Data were collected by a validated questionnaire and gallstone diagnosis was assessed by an experienced radiologist using ultrasonography. Logistic regression model was used to identify the association between selected variables and gallstone disease. RESULTS- The overall prevalence of gallstone in participants was 2.4%. The risk of gallstone was 2.60 times higher in people age 45 and older than those aged 30 - 44 years (Odds Ratio = 2.60, 95% CI; 1.22 - 5.55). Females were 2.73 (95% CI; 1.34 - 5.56) times more likely to have disease compared to males as well. The risk in unmarried individuals was also three times higher than married ones (OR = 2.99- 95% CI 1.02 - 9.16). Additionally, daily physical activity reduced the risk of gallstone disease by 66% (95% CI; 0.18 - 0.86). CONCLUSION- In conclusion, increasing age and female gender were risk factors, whereas daily physical activity and marriage identified as protective factors in aetiology of gallstone disease.

Date: 2016
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