Amniotic Membrane as Allograft for Construction of Neovagina by McIndoe Technique in Vaginal Agenesis

Necip Cihangir Yilanlioglu, Altug Semiz, Yasam Kemal Akpak and Semra Kahraman

Global Journal of Health Science, 2017, vol. 9, issue 4, 31

Abstract: BACKGROUND- To assess the anatomical and functional results of neovagina creation with amniotic membrane.METHODS- We operated on three young women with vaginal agenesis two of whom had a diagnosis of Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome and the other mixed gonadal dysgenesis. The mean age was 29.67 years (range 28-33). A fresh amniotic membrane retrieved from a Cesarean section on the same operation date was prepared over a mould and inserted into the newly formed tunnel between the bladder and the rectum as per McIndoe technique. The patients were followed up for one year minimum. RESULTS- Mean vaginal depth achieved was 8, 10 and 7 cm (average 8.3 cm) at the 12 month follow-up clinic. Two patients expressed having satisfactory sexual life at follow-up interview. One patient who had infrequent coitus and neglected appropriate use of mould needed further follow-up in clinic and self-dilation.CONCLUSİONS- McIndoe vaginoplasty with fresh-homologous amniotic membrane is an effective low-risk procedure. It can produce good results in fairly short time span with modest demand on patient compliance and rare morbidity.

Date: 2017
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