Comparison of Genetic Variations in Zika Virus Isolated From Different Geographic Regions

Jooyeon Park, Jinhwa Jang and Insung Ahn
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Jooyeon Park: Dept. of Big Data Science, University of Science & Technology, Daejeon, Republic of Korea
Jinhwa Jang: Biomedical Prediction Technology Lab, Korea Institute of Science and Technology Information, Yuseong-gu, Republic of Korea
Insung Ahn: University of Science and Technology, Daejeon, Republic of Korea

International Journal of Healthcare Information Systems and Informatics (IJHISI), 2019, vol. 14, issue 3, 29-39

Abstract: The Zika virus (ZIKV) belongs to the genus Flavivirus, together with Dengue virus, yellow fever virus, and West Nile virus. The virus, which was first found in Africa in 1947, has spread across the world owing to a lack of effective drugs or vaccines. The complete genome sequence of ZIKV is now available; it includes three structural and seven non-structure genes arranged in the order of capsid, pre-membrane, envelope, NS1, NS2A, NS2B, NS3, NS4A, NS4B, and NS5. Two geographically distinct lineages are known, i.e., Asian and African, but ZIKV exhibits differences in clinical progression among regions.

Date: 2019
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