An Expert System for Drug Preformulation in a Pharmaceutical Company

K. V. Ramani, M. R. Patel and S. K. Patel
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K. V. Ramani: Indian Institute of Management, Ahmedabad 380 015, India
M. R. Patel: Research and Development, Cadila Laboratories Limited, Ahmedabad 380 008, India
S. K. Patel: Analytical Research Laboratory, Cadila Laboratories Limited, Ahmedabad 380 008, India

Interfaces, 1992, vol. 22, issue 2, 101-108

Abstract: We designed, developed, and implemented a computer-based expert system for Cadila Laboratories to aid pharmaceutical experts in drug preformulations. Drugs, such as tablets, contain many chemicals (called excipients) in addition to the main active drug. A preformulation study identifies compatible excipients and their relative proportions in the final formulation. Our expert system has saved about 35 percent of the total R and D time needed for preformulations. Its success is due to the interest of top management and the excellent support of the R and D staff. It has provided a competitive advantage to Cadila Laboratories over other firms in India.

Keywords: industries: pharmaceutical; decision analysis: applications (search for similar items in EconPapers)
Date: 1992
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