Functional imaging of visual cortical layers and subplate in awake mice with optimized three-photon microscopy

Murat Yildirim, Hiroki Sugihara, Peter T. C. So () and Mriganka Sur ()
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Murat Yildirim: Massachusetts Institute of Technology
Hiroki Sugihara: Massachusetts Institute of Technology
Peter T. C. So: Massachusetts Institute of Technology
Mriganka Sur: Massachusetts Institute of Technology

Nature Communications, 2019, vol. 10, issue 1, 1-12

Abstract: Abstract Two-photon microscopy is used to image neuronal activity, but has severe limitations for studying deeper cortical layers. Here, we developed a custom three-photon microscope optimized to image a vertical column of the cerebral cortex > 1 mm in depth in awake mice with low (

Date: 2019
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DOI: 10.1038/s41467-018-08179-6

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