The use of technical replication for detection of low-level somatic mutations in next-generation sequencing

Junho Kim, Dachan Kim, Jae Seok Lim, Ju Heon Maeng, Hyeonju Son, Hoon-Chul Kang, Hojung Nam, Jeong Ho Lee () and Sangwoo Kim ()
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Junho Kim: Yonsei University College of Medicine
Dachan Kim: Yonsei University College of Medicine
Jae Seok Lim: KAIST
Ju Heon Maeng: Yonsei University College of Medicine
Hyeonju Son: Yonsei University College of Medicine
Hoon-Chul Kang: Yonsei University College of Medicine
Hojung Nam: Gwangju Institute of Science and Technology
Jeong Ho Lee: KAIST
Sangwoo Kim: Yonsei University College of Medicine

Nature Communications, 2019, vol. 10, issue 1, 1-11

Abstract: Abstract Accurate genome-wide detection of somatic mutations with low variant allele frequency (VAF,

Date: 2019
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DOI: 10.1038/s41467-019-09026-y

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