Synergy between the anthocyanin and RDR6/SGS3/DCL4 siRNA pathways expose hidden features of Arabidopsis carbon metabolism

Nan Jiang, Aimer Gutierrez-Diaz, Eric Mukundi, Yun Sun Lee, Blake C. Meyers, Marisa S. Otegui and Erich Grotewold ()
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Nan Jiang: Michigan State University
Aimer Gutierrez-Diaz: Michigan State University
Eric Mukundi: Michigan State University
Yun Sun Lee: Michigan State University
Blake C. Meyers: Donald Danforth Plant Science Center
Marisa S. Otegui: Laboratory of Molecular and Cell Biology, University of Wisconsin-Madison
Erich Grotewold: Michigan State University

Nature Communications, 2020, vol. 11, issue 1, 1-13

Abstract: Abstract Anthocyanin pigments furnish a powerful visual output of the stress and metabolic status of Arabidopsis thaliana plants. Essential for pigment accumulation is TRANSPARENT TESTA19 (TT19), a glutathione S-transferase proposed to bind and stabilize anthocyanins, participating in their vacuolar sequestration, a function conserved across the flowering plants. Here, we report the identification of genetic suppressors that result in anthocyanin accumulation in the absence of TT19. We show that mutations in RDR6, SGS3, or DCL4 suppress the anthocyanin defect of tt19 by pushing carbon towards flavonoid biosynthesis. This effect is not unique to tt19 and extends to at least one other anthocyanin pathway gene mutant. This synergy between mutations in components of the RDR6-SGS3-DCL4 siRNA system and the flavonoid pathway reveals genetic/epigenetic mechanisms regulating metabolic fluxes.

Date: 2020
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Persistent link: https://EconPapers.repec.org/RePEc:nat:natcom:v:11:y:2020:i:1:d:10.1038_s41467-020-16289-3

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DOI: 10.1038/s41467-020-16289-3

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