Multiplying the efficiency and impact of biofortification through metabolic engineering

Dominique Van Der Straeten (), Navreet K. Bhullar, Hans De Steur, Wilhelm Gruissem, Donald MacKenzie, Wolfgang Pfeiffer, Matin Qaim, Inez Slamet-Loedin, Simon Strobbe, Joe Tohme, Kurniawan Rudi Trijatmiko, Hervé Vanderschuren, Marc Van Montagu, Chunyi Zhang and Howarth Bouis
Additional contact information
Dominique Van Der Straeten: Ghent University
Navreet K. Bhullar: Institute of Molecular Plant Biology, ETH Zurich
Hans De Steur: Ghent University
Wilhelm Gruissem: Institute of Molecular Plant Biology, ETH Zurich
Donald MacKenzie: Donald Danforth Plant Science Center
Wolfgang Pfeiffer: HarvestPlus c/o IFPRI
Matin Qaim: University of Goettingen
Inez Slamet-Loedin: International Rice Research Institute
Simon Strobbe: Ghent University
Joe Tohme: International Center for Tropical Agriculture, CIAT
Kurniawan Rudi Trijatmiko: International Rice Research Institute
Hervé Vanderschuren: Department of Biosystems, KU Leuven
Marc Van Montagu: International Plant Biotechnology Outreach
Chunyi Zhang: Chinese Academy of Agricultural Sciences

Nature Communications, 2020, vol. 11, issue 1, 1-10

Abstract: Abstract Ending all forms of hunger by 2030, as set forward in the UN-Sustainable Development Goal 2 (UN-SDG2), is a daunting but essential task, given the limited timeline ahead and the negative global health and socio-economic impact of hunger. Malnutrition or hidden hunger due to micronutrient deficiencies affects about one third of the world population and severely jeopardizes economic development. Staple crop biofortification through gene stacking, using a rational combination of conventional breeding and metabolic engineering strategies, should enable a leap forward within the coming decade. A number of specific actions and policy interventions are proposed to reach this goal.

Date: 2020
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DOI: 10.1038/s41467-020-19020-4

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