3D-printed integrative probeheads for magnetic resonance

Junyao Xie, Xueqiu You (), Yuqing Huang, Zurong Ni, Xinchang Wang, Xingrui Li, Chaoyong Yang, Dechao Zhang, Hong Chen, Huijun Sun () and Zhong Chen ()
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Junyao Xie: Xiamen University
Xueqiu You: Xiamen University
Yuqing Huang: Xiamen University
Zurong Ni: Xiamen University
Xinchang Wang: Xiamen University
Xingrui Li: Xiamen University
Chaoyong Yang: Xiamen University
Dechao Zhang: Xiamen University
Hong Chen: Xiamen University
Huijun Sun: Xiamen University
Zhong Chen: Xiamen University

Nature Communications, 2020, vol. 11, issue 1, 1-11

Abstract: Abstract Magnetic resonance (MR) technology has been widely employed in scientific research, clinical diagnosis and geological survey. However, the fabrication of MR radio frequency probeheads still face difficulties in integration, customization and miniaturization. Here, we utilized 3D printing and liquid metal filling techniques to fabricate integrative radio frequency probeheads for MR experiments. The 3D-printed probehead with micrometer precision generally consists of liquid metal coils, customized sample chambers and radio frequency circuit interfaces. We screened different 3D printing materials and optimized the liquid metals by incorporating metal microparticles. The 3D-printed probeheads are capable of performing both routine and nonconventional MR experiments, including in situ electrochemical analysis, in situ reaction monitoring with continues-flow paramagnetic particles and ions separation, and small-sample MR imaging. Due to the flexibility and accuracy of 3D printing techniques, we can accurately obtain complicated coil geometries at the micrometer scale, shortening the fabrication timescale and extending the application scenarios.

Date: 2020
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DOI: 10.1038/s41467-020-19711-y

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