Photodegradation of carbon dots cause cytotoxicity

Yue-Yue Liu, Nan-Yang Yu, Wen-Di Fang, Qiao-Guo Tan, Rong Ji, Liu-Yan Yang, Si Wei (), Xiao-Wei Zhang () and Ai-Jun Miao ()
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Yue-Yue Liu: Nanjing University
Nan-Yang Yu: Nanjing University
Wen-Di Fang: Nanjing University
Qiao-Guo Tan: Xiamen University
Rong Ji: Nanjing University
Liu-Yan Yang: Nanjing University
Si Wei: Nanjing University
Xiao-Wei Zhang: Nanjing University
Ai-Jun Miao: Nanjing University

Nature Communications, 2021, vol. 12, issue 1, 1-12

Abstract: Abstract Carbon dots (CDs) are photoluminescent nanomaterials with wide-ranging applications. Despite their photoactivity, it remains unknown whether CDs degrade under illumination and whether such photodegradation poses any cytotoxic effects. Here, we show laboratory-synthesized CDs irradiated with light degrade into molecules that are toxic to both normal (HEK-293) and cancerous (HeLa and HepG2) human cells. Eight days of irradiation photolyzes 28.6-59.8% of the CDs to

Date: 2021
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DOI: 10.1038/s41467-021-21080-z

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