A novel art of continuous noninvasive blood pressure measurement

Jürgen Fortin (), Dorothea E. Rogge, Christian Fellner, Doris Flotzinger, Julian Grond, Katja Lerche and Bernd Saugel
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Jürgen Fortin: CNSystems Medizintechnik GmbH
Dorothea E. Rogge: University Medical Center Hamburg-Eppendorf
Christian Fellner: CNSystems Medizintechnik GmbH
Doris Flotzinger: CNSystems Medizintechnik GmbH
Julian Grond: CNSystems Medizintechnik GmbH
Katja Lerche: CNSystems Medizintechnik GmbH
Bernd Saugel: University Medical Center Hamburg-Eppendorf

Nature Communications, 2021, vol. 12, issue 1, 1-14

Abstract: Abstract Wearable sensors to continuously measure blood pressure and derived cardiovascular variables have the potential to revolutionize patient monitoring. Current wearable methods analyzing time components (e.g., pulse transit time) still lack clinical accuracy, whereas existing technologies for direct blood pressure measurement are too bulky. Here we present an innovative art of continuous noninvasive hemodynamic monitoring (CNAP2GO). It directly measures blood pressure by using a volume control technique and could be used for small wearable sensors integrated in a finger-ring. As a software prototype, CNAP2GO showed excellent blood pressure measurement performance in comparison with invasive reference measurements in 46 patients having surgery. The resulting pulsatile blood pressure signal carries information to derive cardiac output and other hemodynamic variables. We show that CNAP2GO can self-calibrate and be miniaturized for wearable approaches. CNAP2GO potentially constitutes the breakthrough for wearable sensors for blood pressure and flow monitoring in both ambulatory and in-hospital clinical settings.

Date: 2021
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Persistent link: https://EconPapers.repec.org/RePEc:nat:natcom:v:12:y:2021:i:1:d:10.1038_s41467-021-21271-8

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DOI: 10.1038/s41467-021-21271-8

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