Ploidy dynamics increase the risk of liver cancer initiation

Miryam Müller, Stephanie May and Thomas G. Bird ()
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Miryam Müller: Cancer Research UK Beatson Institute
Stephanie May: Cancer Research UK Beatson Institute
Thomas G. Bird: Cancer Research UK Beatson Institute

Nature Communications, 2021, vol. 12, issue 1, 1-4

Abstract: Liver cancer typically arises after years of inflammatory insults to hepatocytes. These cells can change their ploidy state during health and disease. Whilst polyploidy may offer some protection, new research shows it may also promote the formation of liver tumours.

Date: 2021
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DOI: 10.1038/s41467-021-21897-8

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