Full spectrum fluorescence lifetime imaging with 0.5 nm spectral and 50 ps temporal resolution

Gareth O. S. Williams, Elvira Williams, Neil Finlayson, Ahmet T. Erdogan, Qiang Wang, Susan Fernandes, Ahsan R. Akram, Kev Dhaliwal, Robert K. Henderson, John M. Girkin () and Mark Bradley ()
Additional contact information
Gareth O. S. Williams: University of Edinburgh
Elvira Williams: Durham University
Neil Finlayson: University of Edinburgh, King’s Buildings
Ahmet T. Erdogan: University of Edinburgh, King’s Buildings
Qiang Wang: University of Edinburgh
Susan Fernandes: University of Edinburgh
Ahsan R. Akram: University of Edinburgh
Kev Dhaliwal: University of Edinburgh
Robert K. Henderson: University of Edinburgh, King’s Buildings
John M. Girkin: Durham University
Mark Bradley: University of Edinburgh

Nature Communications, 2021, vol. 12, issue 1, 1-9

Abstract: Abstract The use of optical techniques to interrogate wide ranging samples from semiconductors to biological tissue for rapid analysis and diagnostics has gained wide adoption over the past decades. The desire to collect ever more spatially, spectrally and temporally detailed optical signatures for sample characterization has specifically driven a sharp rise in new optical microscopy technologies. Here we present a high-speed optical scanning microscope capable of capturing time resolved images across 512 spectral and 32 time channels in a single acquisition with the potential for ~0.2 frames per second (256 × 256 image pixels). Each pixel in the resulting images contains a detailed data cube for the study of diverse time resolved light driven phenomena. This is enabled by integration of system control electronics and on-chip processing which overcomes the challenges presented by high data volume and low imaging speed, often bottlenecks in previous systems.

Date: 2021
References: View references in EconPapers View complete reference list from CitEc
Citations:

Downloads: (external link)
https://www.nature.com/articles/s41467-021-26837-0 Abstract (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:natcom:v:12:y:2021:i:1:d:10.1038_s41467-021-26837-0

Ordering information: This journal article can be ordered from
https://www.nature.com/ncomms/

DOI: 10.1038/s41467-021-26837-0

Access Statistics for this article

Nature Communications is currently edited by Nathalie Le Bot, Enda Bergin and Fiona Gillespie

More articles in Nature Communications from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().