An ionizable lipid toolbox for RNA delivery

Xuexiang Han, Hanwen Zhang, Kamila Butowska, Kelsey L. Swingle, Mohamad-Gabriel Alameh, Drew Weissman and Michael J. Mitchell ()
Additional contact information
Xuexiang Han: University of Pennsylvania
Hanwen Zhang: University of Pennsylvania
Kamila Butowska: University of Pennsylvania
Kelsey L. Swingle: University of Pennsylvania
Mohamad-Gabriel Alameh: University of Pennsylvania
Drew Weissman: University of Pennsylvania
Michael J. Mitchell: University of Pennsylvania

Nature Communications, 2021, vol. 12, issue 1, 1-6

Abstract: Recent years have witnessed incredible growth in RNA therapeutics, which has benefited significantly from decades of research on lipid nanoparticles, specifically its key component—the ionizable lipid. This comment discusses the major ionizable lipid types, and provides perspectives for future development.

Date: 2021
References: View references in EconPapers View complete reference list from CitEc
Citations: View citations in EconPapers (5)

Downloads: (external link)
https://www.nature.com/articles/s41467-021-27493-0 Abstract (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:natcom:v:12:y:2021:i:1:d:10.1038_s41467-021-27493-0

Ordering information: This journal article can be ordered from
https://www.nature.com/ncomms/

DOI: 10.1038/s41467-021-27493-0

Access Statistics for this article

Nature Communications is currently edited by Nathalie Le Bot, Enda Bergin and Fiona Gillespie

More articles in Nature Communications from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().