Unmixing for ultra-high-plex fluorescence imaging

Archibald Enninful, Alev Baysoy and Rong Fan ()
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Archibald Enninful: Yale University
Alev Baysoy: Yale University
Rong Fan: Yale University

Nature Communications, 2022, vol. 13, issue 1, 1-3

Abstract: Writing in Nature communications, Seo and collaborators presented PICASSO as a method to achieve 15-color imaging of spatially overlapping proteins using no reference emission spectra in a single staining and imaging round. This accessible tool has the potential to be applied to diverse applications within the spatial biology field without neglecting accuracy.

Date: 2022
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DOI: 10.1038/s41467-022-31110-z

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