Real-time 3D analysis during electron tomography using tomviz

Jonathan Schwartz, Chris Harris, Jacob Pietryga, Huihuo Zheng, Prashant Kumar, Anastasiia Visheratina, Nicholas A. Kotov, Brianna Major, Patrick Avery, Peter Ercius, Utkarsh Ayachit, Berk Geveci, David A. Muller, Alessandro Genova, Yi Jiang, Marcus Hanwell and Robert Hovden ()
Additional contact information
Jonathan Schwartz: University of Michigan
Chris Harris: Kitware Inc
Jacob Pietryga: University of Michigan
Huihuo Zheng: Argonne National Laboratory
Prashant Kumar: University of Michigan
Anastasiia Visheratina: University of Michigan
Nicholas A. Kotov: University of Michigan
Brianna Major: Kitware Inc
Patrick Avery: Kitware Inc
Peter Ercius: Lawrence Berkeley National Laboratory
Utkarsh Ayachit: Kitware Inc
Berk Geveci: Kitware Inc
David A. Muller: Cornell University
Alessandro Genova: Kitware Inc
Yi Jiang: Argonne National Laboratory
Marcus Hanwell: Kitware Inc
Robert Hovden: University of Michigan

Nature Communications, 2022, vol. 13, issue 1, 1-7

Abstract: Abstract The demand for high-throughput electron tomography is rapidly increasing in biological and material sciences. However, this 3D imaging technique is computationally bottlenecked by alignment and reconstruction which runs from hours to days. We demonstrate real-time tomography with dynamic 3D tomographic visualization to enable rapid interpretation of specimen structure immediately as data is collected on an electron microscope. Using geometrically complex chiral nanoparticles, we show volumetric interpretation can begin in less than 10 minutes and a high-quality tomogram is available within 30 minutes. Real-time tomography is integrated into tomviz, an open-source and cross-platform 3D data analysis tool that contains intuitive graphical user interfaces (GUI), to enable any scientist to characterize biological and material structure in 3D.

Date: 2022
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Persistent link: https://EconPapers.repec.org/RePEc:nat:natcom:v:13:y:2022:i:1:d:10.1038_s41467-022-32046-0

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DOI: 10.1038/s41467-022-32046-0

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