Regulating voltage-gated ion channels with nanobodies

Declan Manning and L. Fernando Santana ()
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Declan Manning: University of California, Davis, One Shields Avenue
L. Fernando Santana: University of California, Davis, One Shields Avenue

Nature Communications, 2022, vol. 13, issue 1, 1-2

Abstract: In this work, Morgenstern and colleagues describe an approach involving functionalized nanobodies which decrease the activity of voltage-gated Ca2+ channels associated with β1 subunits and promote their removal from the surface membrane of neurons and muscle.

Date: 2022
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DOI: 10.1038/s41467-022-35027-5

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