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Quantifying the direct and indirect protection provided by insecticide treated bed nets against malaria

H. Juliette T. Unwin (), Ellie Sherrard-Smith, Thomas S. Churcher and Azra C. Ghani
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H. Juliette T. Unwin: Faculty of Medicine, Imperial College London
Ellie Sherrard-Smith: Faculty of Medicine, Imperial College London
Thomas S. Churcher: Faculty of Medicine, Imperial College London
Azra C. Ghani: Faculty of Medicine, Imperial College London

Nature Communications, 2023, vol. 14, issue 1, 1-12

Abstract: Abstract Long lasting insecticidal nets (LLINs) provide both direct and indirect protection against malaria. As pyrethroid resistance evolves in mosquito vectors, it will be useful to understand how the specific benefits LLINs afford individuals and communities may be affected. Here we use modelling to show that there is no minimum LLIN usage needed for users and non-users to benefit from community protection. Modelling results also indicate that pyrethroid resistance in local mosquitoes will likely diminish the direct and indirect benefits from insecticides, leaving the barrier effects intact, but LLINs are still expected to provide enhanced benefit over untreated nets even at high levels of pyrethroid resistance.

Date: 2023
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Persistent link: https://EconPapers.repec.org/RePEc:nat:natcom:v:14:y:2023:i:1:d:10.1038_s41467-023-36356-9

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DOI: 10.1038/s41467-023-36356-9

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